PFI-3, 99.63%
cas: 1819363-80-8 — see every product listed under this CAS number, including other names
PFI-3, 99.63% (CAS 1819363-80-8) is a chemical reagent available from Chemat. Available pack sizes: 10mM/1mL, 5 mg, 50 mg, 1 mg, 10 mg. Offered by: MedChemExpress.
| brand | MedChemExpress |
|---|---|
| catalog number | HY-12409-10mM/1mL |
| cas | 1819363-80-8 |
| size | 10mM/1mL |
| availability | In stock |
Need more information?
Ask us about this product — we're happy to help.
Available pack sizes
| brand | size | price | |
|---|---|---|---|
| MedChemExpress | 10mM/1mL | 570.47 Pln | |
| MedChemExpress | 5 mg | 528.67 Pln | |
| MedChemExpress | 50 mg | 2037.97 Pln | |
| MedChemExpress | 1 mg | 319.69 Pln | |
| MedChemExpress | 10 mg | 793.38 Pln |
properties
| delivery time | 1-2 weeks |
|---|---|
| purity | 99.63% |
PFI-3 is an azabicycloalkane that is (1R,4R)-2,5-diazabicyclo[2.2.1]heptane which is substituted at position 2 by a 3-(2-hydroxyphenyl)-3-oxoprop-1-en-1-yl group and at position 5 by a pyridin-2-yl group. It is a potent and selective inhibitor of polybromo 1 (Kd = 48 nM), SMARCA2 and SMARCA4 (Kd = 89 nM) bromodomains. It is a member of pyridines, a member of phenols, an azabicycloalkane and an enone.
Source: ChEBI
| Molecular formula | C19H19N3O2 |
|---|---|
| Molecular weight | 321.4 g/mol |
| IUPAC name | (E)-1-(2-hydroxyphenyl)-3-[(1R,4R)-5-pyridin-2-yl-2,5-diazabicyclo[2.2.1]heptan-2-yl]prop-2-en-1-one |
| InChIKey | INAICWLVUAKEPB-QSTFCLMHSA-N |
| SMILES | C1[C@@H]2CN([C@H]1CN2C3=CC=CC=N3)/C=C/C(=O)C4=CC=CC=C4O |
Computed by PubChem (NCBI)