PLERIXAFOR
cas: 110078-46-1 — see every product listed under this CAS number, including other names
PLERIXAFOR (CAS 110078-46-1) is a chemical reagent available from Chemat. Available pack sizes: on request, 250mg, 50mg, 100mg, 500mg. Offered by: Chemat Brand, Mikromol, Biosynth.
| brand | Chemat Brand |
|---|---|
| catalog number | AO-P0107.00 |
| cas | 110078-46-1 |
| size | on request |
| availability | In stock |
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Available pack sizes
| brand | size | price | |
|---|---|---|---|
| Chemat Brand | on request | price on request | |
| Mikromol | 250mg | price on request | |
| Biosynth | 50mg | price on request | |
| Biosynth | 100mg | price on request | |
| Biosynth | 250mg | price on request | |
| Biosynth | 500mg | price on request |
properties
| delivery time | To be confirmed by Chemat |
|---|---|
| purity | No data |
Plerixafor is an azamacrocycle consisting of two cyclam rings connected by a 1,4-phenylenebis(methylene) linker. It is a CXCR4 chemokine receptor antagonist and a hematopoietic stem cell mobilizer. It is used in combination with grulocyte-colony stimulating factor (G-CSF) to mobilize hematopoietic stem cells to the perpheral blood for collection and subsequent autologous transplantation in patients with non-Hodgkin's lymphoma and multiple myeloma. It has a role as a C-X-C chemokine receptor type 4 antagonist, an antineoplastic agent, an immunological adjuvant and an anti-HIV agent. It is a member of benzenes, a crown amine, an azacycloalkane, a secondary amino compound, a tertiary amino compound and an azamacrocycle. It is functionally related to a 1,4,8,11-tetraazacyclotetradecane.
Source: ChEBI
| Molecular formula | C28H54N8 |
|---|---|
| Molecular weight | 502.8 g/mol |
| IUPAC name | 1-[[4-(1,4,8,11-tetrazacyclotetradec-1-ylmethyl)phenyl]methyl]-1,4,8,11-tetrazacyclotetradecane |
| InChIKey | YIQPUIGJQJDJOS-UHFFFAOYSA-N |
| SMILES | C1CNCCNCCCN(CCNC1)CC2=CC=C(C=C2)CN3CCCNCCNCCCNCC3 |
Computed by PubChem (NCBI)
Synonyms:
Plerixafor, Mozobil, Amd 3100, plerixaforum, 1,1'-[1,4-Phenylenebis(methylene)]bis-1,4,8,11-tetraazacyclotetradecane, 1,4,8,11-Tetraazacyclotetradecane, 1,1'-(1,4-phenylenebis(methylene))bis-, mezobil, RPA bicyclam, 1,4,8,11-Tetraazacyclotetradecane, 1,1'-[1,4-phenylenebis(methylene)]bis-, 1,1'-(1,4-Phenylenebis(methylene))-bis-1,4,8,11-tetraazacyclotetradecane