Plerixafor (AMD3100)
cas: 110078-46-1 — see every product listed under this CAS number, including other names
Plerixafor (AMD3100) (CAS 110078-46-1) is a chemical reagent available from Chemat. Available pack sizes: 100mg, 25mg, 10mM (in 1ml ethanol), 50mg. Offered by: GLPBio.
| brand | GLPBio |
|---|---|
| catalog number | GC14745-100 |
| cas | 110078-46-1 |
| size | 100mg |
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Available pack sizes
| brand | size | price | |
|---|---|---|---|
| GLPBio | 100mg | 1659.51 Pln | |
| GLPBio | 25mg | 779.58 Pln | |
| GLPBio | 10mM (in 1ml ethanol) | 573.64 Pln | |
| GLPBio | 50mg | 1041.69 Pln |
properties
| purity | No data |
|---|---|
| delivery time | To be confirmed by Chemat |
Plerixafor is an azamacrocycle consisting of two cyclam rings connected by a 1,4-phenylenebis(methylene) linker. It is a CXCR4 chemokine receptor antagonist and a hematopoietic stem cell mobilizer. It is used in combination with grulocyte-colony stimulating factor (G-CSF) to mobilize hematopoietic stem cells to the perpheral blood for collection and subsequent autologous transplantation in patients with non-Hodgkin's lymphoma and multiple myeloma. It has a role as a C-X-C chemokine receptor type 4 antagonist, an antineoplastic agent, an immunological adjuvant and an anti-HIV agent. It is a member of benzenes, a crown amine, an azacycloalkane, a secondary amino compound, a tertiary amino compound and an azamacrocycle. It is functionally related to a 1,4,8,11-tetraazacyclotetradecane.
Source: ChEBI
| Molecular formula | C28H54N8 |
|---|---|
| Molecular weight | 502.8 g/mol |
| IUPAC name | 1-[[4-(1,4,8,11-tetrazacyclotetradec-1-ylmethyl)phenyl]methyl]-1,4,8,11-tetrazacyclotetradecane |
| InChIKey | YIQPUIGJQJDJOS-UHFFFAOYSA-N |
| SMILES | C1CNCCNCCCN(CCNC1)CC2=CC=C(C=C2)CN3CCCNCCNCCCNCC3 |
Computed by PubChem (NCBI)
Synonyms:
Plerixafor, Mozobil, Amd 3100, plerixaforum, 1,1'-[1,4-Phenylenebis(methylene)]bis-1,4,8,11-tetraazacyclotetradecane, 1,4,8,11-Tetraazacyclotetradecane, 1,1'-(1,4-phenylenebis(methylene))bis-, mezobil, RPA bicyclam, 1,4,8,11-Tetraazacyclotetradecane, 1,1'-[1,4-phenylenebis(methylene)]bis-, 1,1'-(1,4-Phenylenebis(methylene))-bis-1,4,8,11-tetraazacyclotetradecane