Products 110078-46-1

CAS 110078-46-1 appears in our catalog under these names: PLERIXAFOR, Plerixafor, >95% (HPLC), Plerixafor (AMD3100), Plerixafor/ 100%, Plerixafor, >98.0%(GC). Offered by: Chemat Brand, TRC, Mikromol, GLPBio, TargetMol. Available pack sizes: on request, 100mg, 25mg, 50mg, 250mg, 10mM (in 1ml ethanol), 5mg, 10mg.

PLERIXAFOR
Chemat Brand, Mikromol, Biosynth
  • size: on request, 250mg, 50mg, 100mg
  • Variants: 6
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Plerixafor, >95% (HPLC)
TRC
  • size: 100mg, 25mg, 50mg
  • Variants: 3
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Plerixafor (AMD3100)
GLPBio
  • size: 100mg, 25mg, 10mM (in 1ml ethanol), 50mg
  • Variants: 4
from 573.64
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Plerixafor/ 100%
TargetMol
  • size: 5mg, 10mg, 25mg, 50mg
  • Variants: 7
from 458.82
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Plerixafor, >98.0%(GC)
TCI
  • size: 50mg, 250mg
  • Variants: 2
from 334.70
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Plerixafor, 98.00%
Chemat
  • size: 100mg
  • Variants: 1
from 842.53
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Plerixafor 99%
Ambeed
  • size: 10g, 1mg, 10mg, 100mg
  • Variants: 7
from 147.88
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1,4-Bis((1,4,8,11-tetraazacyclotetradecan-1-yl)methyl)benzene, 99%, 99%
Chemat
  • size: 10mg, 50mg, 100mg, 250mg
  • Variants: 6
from 78.80
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Plerixafor, 99.90%
MedChemExpress
  • size: 25 mg, 100 mg, 50 mg, 5 mg
  • Variants: 5
from 380.06
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Plerixafor (Standard)
MedChemExpress
  • size: 25 mg, 50 mg, 5 mg, 10 mg
  • Variants: 5
from 765.52
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1,4-Bis((1,4,8,11-tetraazacyclotetradecan-1-yl)methyl)benzene, 95+%
Fluorochem
  • size: 5mg, 100mg, 250mg, 1g
  • Variants: 6
from 310.33
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Plerixafor-d4
Chemat Brand
  • size: on request
  • Variants: 1
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Structural formula: {0} (CAS {1})

Plerixafor is an azamacrocycle consisting of two cyclam rings connected by a 1,4-phenylenebis(methylene) linker. It is a CXCR4 chemokine receptor antagonist and a hematopoietic stem cell mobilizer. It is used in combination with grulocyte-colony stimulating factor (G-CSF) to mobilize hematopoietic stem cells to the perpheral blood for collection and subsequent autologous transplantation in patients with non-Hodgkin's lymphoma and multiple myeloma. It has a role as a C-X-C chemokine receptor type 4 antagonist, an antineoplastic agent, an immunological adjuvant and an anti-HIV agent. It is a member of benzenes, a crown amine, an azacycloalkane, a secondary amino compound, a tertiary amino compound and an azamacrocycle. It is functionally related to a 1,4,8,11-tetraazacyclotetradecane.

Source: ChEBI

Identity
Molecular formulaC28H54N8
Molecular weight502.8 g/mol
IUPAC name1-[[4-(1,4,8,11-tetrazacyclotetradec-1-ylmethyl)phenyl]methyl]-1,4,8,11-tetrazacyclotetradecane
InChIKeyYIQPUIGJQJDJOS-UHFFFAOYSA-N
SMILESC1CNCCNCCCN(CCNC1)CC2=CC=C(C=C2)CN3CCCNCCNCCCNCC3

Computed by PubChem (NCBI)

Synonyms: Plerixafor, Mozobil, Amd 3100, plerixaforum, 1,1'-[1,4-Phenylenebis(methylene)]bis-1,4,8,11-tetraazacyclotetradecane, 1,4,8,11-Tetraazacyclotetradecane, 1,1'-(1,4-phenylenebis(methylene))bis-, mezobil, RPA bicyclam, 1,4,8,11-Tetraazacyclotetradecane, 1,1'-[1,4-phenylenebis(methylene)]bis-, 1,1'-(1,4-Phenylenebis(methylene))-bis-1,4,8,11-tetraazacyclotetradecane