Products 172889-27-9
CAS 172889-27-9 appears in our catalog under these names: PP2, PP 2 (AG 1879), PP2/ 95.65% (existing batch purity), PP 2, >97.0%(HPLC)(T), PP2 98%. Offered by: TRC, GLPBio, TargetMol, TCI, Chemat. Available pack sizes: 100mg, 10mg, 5mg, 10mM (in 1ml dmso), 50mg, 2mg, 25mg, 200mg.
PP2 is a member of the class of pyrazolopyrimidine that is pyrazolo[3,4-d]pyrimidin-4-amine bearing additional tert-butyl and 4-chlorophenyl substituents at positions 1 and 3 respectively. It is a potent ATP-competitive inhibitor of the Src family of protein tyrosine kinases. It has a role as a geroprotector, a beta-adrenergic antagonist and an EC 2.7.10.2 (non-specific protein-tyrosine kinase) inhibitor. It is an aromatic amine, a pyrazolopyrimidine and a member of monochlorobenzenes.
Source: ChEBI
| Molecular formula | C15H16ClN5 |
|---|---|
| Molecular weight | 301.77 g/mol |
| IUPAC name | 1-tert-butyl-3-(4-chlorophenyl)pyrazolo[3,4-d]pyrimidin-4-amine |
| InChIKey | PBBRWFOVCUAONR-UHFFFAOYSA-N |
| SMILES | CC(C)(C)N1C2=NC=NC(=C2C(=N1)C3=CC=C(C=C3)Cl)N |
Computed by PubChem (NCBI)
Synonyms:
3-(4-Chlorophenyl)-1-(1,1-dimethylethyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine, 3-(4-chlorophenyl)-1-(1,1-dimethylethyl)-1h-pyrazolo(3,4-d)pyrimidin-4-amine, 3-CDPPA cpd, pp2, 1-(tert-butyl)-3-(4-chlorophenyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine, Src kinase inhibitor PP2, 1-tert-butyl-3-(4-chlorophenyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine, 1-tert-butyl-3-(4-chlorophenyl)pyrazolo[3,4-d]pyrimidin-4-amine, 4few, 4-Amino-5-(4-chlorophenyl)-7-(t-butyl)pyrazolo[3,4-d]pyrimidine