Palovarotene, 99.49%

cas: 410528-02-8 — see every product listed under this CAS number, including other names

Palovarotene, 99.49% (CAS 410528-02-8) is a chemical reagent available from Chemat. Available pack sizes: 25 mg, 10mM/1mL, 10 mg, 50 mg, 5 mg, 100 mg. Offered by: MedChemExpress.

brandMedChemExpress
catalog numberHY-14799-25 mg
cas410528-02-8
size25 mg
availability In stock
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Available pack sizes

brand size price
MedChemExpress 25 mg 1452.83 Pln
MedChemExpress 10mM/1mL 472.94 Pln
MedChemExpress 10 mg 677.28 Pln
MedChemExpress 50 mg 2256.24 Pln
MedChemExpress 5 mg 445.08 Pln
MedChemExpress 100 mg 3324.36 Pln

properties

delivery time 1-2 weeks
purity99.49%
Structural formula: {0} (CAS {1})

Palovarotene is an olefinic compound that is ethene is which a hydrogen at position 1 is replaced by a 4-carboxyphenyl group and a hydrogen at position 2 is replaced by a 5,5,8,8-tetramethyl-3-[(1H-pyrazol-1-yl)methyl]-5,6,7,8-tetrahydronaphthalen-2-yl group (the E-stereoisomer). It is a selective retinoic acid receptor gamma (RARgamma) agonist developed by Ipsen, to reduce the formation of new heterotopic ossification in adults and children with fibrodysplasia ossificans progressiva (FOP), a rare bone disorder. It has a role as a retinoic acid receptor gamma agonist. It is a member of benzoic acids, a member of pyrazoles, a stilbenoid, a member of tetralins and an olefinic compound.

Source: ChEBI

Identity
Molecular formulaC27H30N2O2
Molecular weight414.5 g/mol
IUPAC name4-[(E)-2-[5,5,8,8-tetramethyl-3-(pyrazol-1-ylmethyl)-6,7-dihydronaphthalen-2-yl]ethenyl]benzoic acid
InChIKeyYTFHCXIPDIHOIA-DHZHZOJOSA-N
SMILESCC1(CCC(C2=C1C=C(C(=C2)/C=C/C3=CC=C(C=C3)C(=O)O)CN4C=CC=N4)(C)C)C

Computed by PubChem (NCBI)

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