Palovarotene
cas: 410528-02-8 — see every product listed under this CAS number, including other names
Palovarotene (CAS 410528-02-8) is a chemical reagent available from Chemat. Available pack sizes: on request, 1mg, 10mg, 5mg, 10mM (in 1ml dmso), 50mg. Offered by: Chemat Brand, GLPBio.
| brand | Chemat Brand |
|---|---|
| catalog number | ULP100002 |
| cas | 410528-02-8 |
| size | on request |
| availability | Do potwierdzenia przez Chemat|To be confirmed by Chemat |
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Available pack sizes
| brand | size | price | |
|---|---|---|---|
| Chemat Brand | on request | price on request | |
| GLPBio | 1mg | 625.12 Pln | |
| GLPBio | 10mg | 1168.06 Pln | |
| GLPBio | 5mg | 873.19 Pln | |
| GLPBio | 10mM (in 1ml dmso) | 919.99 Pln | |
| GLPBio | 50mg | 2970.05 Pln |
properties
| purity | No data |
|---|---|
| category | Chemicals |
| delivery time | To be confirmed by Chemat |
Palovarotene is an olefinic compound that is ethene is which a hydrogen at position 1 is replaced by a 4-carboxyphenyl group and a hydrogen at position 2 is replaced by a 5,5,8,8-tetramethyl-3-[(1H-pyrazol-1-yl)methyl]-5,6,7,8-tetrahydronaphthalen-2-yl group (the E-stereoisomer). It is a selective retinoic acid receptor gamma (RARgamma) agonist developed by Ipsen, to reduce the formation of new heterotopic ossification in adults and children with fibrodysplasia ossificans progressiva (FOP), a rare bone disorder. It has a role as a retinoic acid receptor gamma agonist. It is a member of benzoic acids, a member of pyrazoles, a stilbenoid, a member of tetralins and an olefinic compound.
Source: ChEBI
| Molecular formula | C27H30N2O2 |
|---|---|
| Molecular weight | 414.5 g/mol |
| IUPAC name | 4-[(E)-2-[5,5,8,8-tetramethyl-3-(pyrazol-1-ylmethyl)-6,7-dihydronaphthalen-2-yl]ethenyl]benzoic acid |
| InChIKey | YTFHCXIPDIHOIA-DHZHZOJOSA-N |
| SMILES | CC1(CCC(C2=C1C=C(C(=C2)/C=C/C3=CC=C(C=C3)C(=O)O)CN4C=CC=N4)(C)C)C |
Computed by PubChem (NCBI)