cas: 449811-01-2 — see every product listed under this CAS number, including other names
Pamapimod (Standard) (CAS 449811-01-2) is a chemical reagent available from Chemat. Available pack sizes: 50 mg, 100 mg, 5 mg, 25 mg, 10 mg, 1 mg. Offered by: MedChemExpress.
| brand | MedChemExpress |
|---|---|
| catalog number | HY-10405R-50 mg |
| cas | 449811-01-2 |
| size | 50 mg |
| availability | Get quote |
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| brand | size | price | |
|---|---|---|---|
| MedChemExpress | 50 mg | 7490.03 Pln | |
| MedChemExpress | 100 mg | 10434.32 Pln | |
| MedChemExpress | 5 mg | 1559.64 Pln | |
| MedChemExpress | 25 mg | 4726.85 Pln | |
| MedChemExpress | 10 mg | 2423.42 Pln | |
| MedChemExpress | 1 mg | 719.08 Pln |
| delivery time | over 3 weeks |
|---|---|
| purity | no data |
Pamapimod is a member of the class of pyridopyrimidines that is 8-methylpyrido[2,3-d]pyrimidin-7(8H)-one carrying additional (1,5-dihydroxypentan-3-yl)amino and 2,4-difluorophenoxy substituents at positions 2 and 6 respectively. It is a potent inhibitor of MAPK and is used for treatment of rheumatoid arthritis. It has a role as an antirheumatic drug and an EC 2.7.11.24 (mitogen-activated protein kinase) inhibitor. It is a primary alcohol, a diol, an aromatic amine, an aromatic ether, a difluorobenzene, a pyridopyrimidine and a secondary amino compound.
Source: ChEBI
| Molecular formula | C19H20F2N4O4 |
|---|---|
| Molecular weight | 406.4 g/mol |
| IUPAC name | 6-(2,4-difluorophenoxy)-2-(1,5-dihydroxypentan-3-ylamino)-8-methylpyrido[2,3-d]pyrimidin-7-one |
| InChIKey | JYYLVUFNAHSSFE-UHFFFAOYSA-N |
| SMILES | CN1C2=NC(=NC=C2C=C(C1=O)OC3=C(C=C(C=C3)F)F)NC(CCO)CCO |
Computed by PubChem (NCBI)