Pamapimod
cas: 449811-01-2 — see every product listed under this CAS number, including other names
Pamapimod (CAS 449811-01-2) is a chemical reagent available from Chemat. Available pack sizes: on request, 1mg, 2mg, 5mg. Offered by: Chemat Brand, TRC.
| brand | Chemat Brand |
|---|---|
| catalog number | ULP119001 |
| cas | 449811-01-2 |
| size | on request |
| availability | Do potwierdzenia przez Chemat|To be confirmed by Chemat |
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Available pack sizes
| brand | size | price | |
|---|---|---|---|
| Chemat Brand | on request | price on request | |
| TRC | 1mg | price on request | |
| TRC | 2mg | price on request | |
| TRC | 5mg | price on request |
properties
| purity | No data |
|---|---|
| category | Chemicals |
| delivery time | To be confirmed by Chemat |
Pamapimod is a member of the class of pyridopyrimidines that is 8-methylpyrido[2,3-d]pyrimidin-7(8H)-one carrying additional (1,5-dihydroxypentan-3-yl)amino and 2,4-difluorophenoxy substituents at positions 2 and 6 respectively. It is a potent inhibitor of MAPK and is used for treatment of rheumatoid arthritis. It has a role as an antirheumatic drug and an EC 2.7.11.24 (mitogen-activated protein kinase) inhibitor. It is a primary alcohol, a diol, an aromatic amine, an aromatic ether, a difluorobenzene, a pyridopyrimidine and a secondary amino compound.
Source: ChEBI
| Molecular formula | C19H20F2N4O4 |
|---|---|
| Molecular weight | 406.4 g/mol |
| IUPAC name | 6-(2,4-difluorophenoxy)-2-(1,5-dihydroxypentan-3-ylamino)-8-methylpyrido[2,3-d]pyrimidin-7-one |
| InChIKey | JYYLVUFNAHSSFE-UHFFFAOYSA-N |
| SMILES | CN1C2=NC(=NC=C2C=C(C1=O)OC3=C(C=C(C=C3)F)F)NC(CCO)CCO |
Computed by PubChem (NCBI)