Pemetrexed - Bio-X â„¢
cas: 137281-23-3 — see every product listed under this CAS number, including other names
Pemetrexed - Bio-X â„¢ (CAS 137281-23-3) is a chemical reagent available from Chemat. Available pack sizes: 50mg. Offered by: Biosynth.
| brand | Biosynth |
|---|---|
| catalog number | BP164240-50mg |
| cas | 137281-23-3 |
| size | 50mg |
Need more information?
Ask us about this product — we're happy to help.
Available pack sizes
| brand | size | price | |
|---|---|---|---|
| Biosynth | 50mg | price on request |
properties
| category | Life Sciences |
|---|---|
| sub-category 1 | Ligands |
| sub-category 2 | Enzyme Modulators |
| purity | No data |
| delivery time | 1-2 weeks |
Pemetrexed is an N-acylglutamic acid in which the N-acyl group is specified as 4-[2-(2-amino-4-oxo-4,7-dihydro-1H-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl]benzoyl. Inhibits thymidylate synthase (TS), 421 dihydrofolate reductase (DHFR), and glycinamide ribonucleotide formyltransferase (GARFT). It has a role as an antimetabolite, an antineoplastic agent, an EC 1.5.1.3 (dihydrofolate reductase) inhibitor, an EC 2.1.1.45 (thymidylate synthase) inhibitor and an EC 2.1.2.2 (phosphoribosylglycinamide formyltransferase) inhibitor. It is a N-acyl-L-glutamic acid and a pyrrolopyrimidine. It is a conjugate acid of a pemetrexed(2-).
Source: ChEBI
| Molecular formula | C20H21N5O6 |
|---|---|
| Molecular weight | 427.4 g/mol |
| IUPAC name | (2S)-2-[[4-[2-(2-amino-4-oxo-3,7-dihydropyrrolo[2,3-d]pyrimidin-5-yl)ethyl]benzoyl]amino]pentanedioic acid |
| InChIKey | WBXPDJSOTKVWSJ-ZDUSSCGKSA-N |
| SMILES | C1=CC(=CC=C1CCC2=CNC3=C2C(=O)NC(=N3)N)C(=O)N[C@@H](CCC(=O)O)C(=O)O |
Computed by PubChem (NCBI)