Pemetrexed
cas: 137281-23-3 — see every product listed under this CAS number, including other names
Pemetrexed (CAS 137281-23-3) is a chemical reagent available from Chemat. Available pack sizes: on request, 1g, 2g, 5g, 10g, 25g. Offered by: Chemat Brand, Biosynth.
| brand | Chemat Brand |
|---|---|
| catalog number | ULP681 |
| cas | 137281-23-3 |
| size | on request |
| availability | Do potwierdzenia przez Chemat|To be confirmed by Chemat |
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Available pack sizes
| brand | size | price | |
|---|---|---|---|
| Chemat Brand | on request | price on request | |
| Biosynth | 1g | price on request | |
| Biosynth | 2g | price on request | |
| Biosynth | 5g | price on request | |
| Biosynth | 10g | price on request | |
| Biosynth | 25g | price on request |
properties
| purity | No data |
|---|---|
| category | Chemicals |
| delivery time | To be confirmed by Chemat |
Pemetrexed is an N-acylglutamic acid in which the N-acyl group is specified as 4-[2-(2-amino-4-oxo-4,7-dihydro-1H-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl]benzoyl. Inhibits thymidylate synthase (TS), 421 dihydrofolate reductase (DHFR), and glycinamide ribonucleotide formyltransferase (GARFT). It has a role as an antimetabolite, an antineoplastic agent, an EC 1.5.1.3 (dihydrofolate reductase) inhibitor, an EC 2.1.1.45 (thymidylate synthase) inhibitor and an EC 2.1.2.2 (phosphoribosylglycinamide formyltransferase) inhibitor. It is a N-acyl-L-glutamic acid and a pyrrolopyrimidine. It is a conjugate acid of a pemetrexed(2-).
Source: ChEBI
| Molecular formula | C20H21N5O6 |
|---|---|
| Molecular weight | 427.4 g/mol |
| IUPAC name | (2S)-2-[[4-[2-(2-amino-4-oxo-3,7-dihydropyrrolo[2,3-d]pyrimidin-5-yl)ethyl]benzoyl]amino]pentanedioic acid |
| InChIKey | WBXPDJSOTKVWSJ-ZDUSSCGKSA-N |
| SMILES | C1=CC(=CC=C1CCC2=CNC3=C2C(=O)NC(=N3)N)C(=O)N[C@@H](CCC(=O)O)C(=O)O |
Computed by PubChem (NCBI)