Pevonedistat 98%
cas: 905579-51-3 — see every product listed under this CAS number, including other names
Pevonedistat 98% (CAS 905579-51-3) is a chemical reagent available from Chemat. Available pack sizes: 1g, 1mg, 5mg, 10mg, 25mg, 50mg, 100mg, 250mg. Offered by: Ambeed.
| brand | Ambeed |
|---|---|
| catalog number | A724332-1g |
| cas | 905579-51-3 |
| size | 1g |
Documents:
Safety Data Sheet (MSDS)
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Available pack sizes
| brand | size | price | |
|---|---|---|---|
| Ambeed | 1g | 21124.06 Pln | |
| Ambeed | 1mg | 242.44 Pln | |
| Ambeed | 5mg | 476.06 Pln | |
| Ambeed | 10mg | 759.75 Pln | |
| Ambeed | 25mg | 1371.62 Pln | |
| Ambeed | 50mg | 2406.25 Pln | |
| Ambeed | 100mg | 3724.56 Pln | |
| Ambeed | 250mg | 6650.44 Pln |
properties
| purity | 98% |
|---|---|
| delivery time | 1-2 weeks |
| ambeed catalog no. | A724332 |
Pevonedistat is a pyrrolopyrimidine that is 7H-pyrrolo[2,3-d]pyrimidine which is substituted by a (1S)-2,3-dihydro-1H-inden-1-ylnitrilo group at position 4 and by a (1S,3S,4S)-3-hydroxy-4-[(sulfamoyloxy)methyl]cyclopentyl group at position 7. It is a potent and selective NEDD8-activating enzyme inhibitor with an IC50 of 4.7 nM, and currently under clinical investigation for the treatment of acute myeloid leukemia (AML) and myelodysplastic syndromes. It has a role as an antineoplastic agent and an apoptosis inducer. It is a member of cyclopentanols, a pyrrolopyrimidine, a member of indanes, a secondary amino compound and a sulfamidate.
Source: ChEBI
| Molecular formula | C21H25N5O4S |
|---|---|
| Molecular weight | 443.5 g/mol |
| IUPAC name | [(1S,2S,4R)-4-[4-[[(1S)-2,3-dihydro-1H-inden-1-yl]amino]pyrrolo[2,3-d]pyrimidin-7-yl]-2-hydroxycyclopentyl]methyl sulfamate |
| InChIKey | MPUQHZXIXSTTDU-QXGSTGNESA-N |
| SMILES | C1CC2=CC=CC=C2[C@H]1NC3=C4C=CN(C4=NC=N3)[C@@H]5C[C@H]([C@H](C5)O)COS(=O)(=O)N |
Computed by PubChem (NCBI)