Picropodophyllotoxin

cas: 477-47-4 — see every product listed under this CAS number, including other names

Picropodophyllotoxin (CAS 477-47-4) is a chemical reagent available from Chemat. Available pack sizes: on request, 10mg. Offered by: Chemat Brand, Chemat.

brandChemat Brand
catalog numberULP122012
cas477-47-4
sizeon request
availability Do potwierdzenia przez Chemat|To be confirmed by Chemat
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Available pack sizes

brand size price
Chemat Brand on request price on request
Chemat 10mg 678.61 Pln

properties

purityNo data
categoryChemicals
delivery timeTo be confirmed by Chemat
Structural formula: {0} (CAS {1})

Picropodophyllotoxin is an organic heterotetracyclic compound that has a furonaphthodioxole skeleton bearing 3,4,5-trimethoxyphenyl and hydroxy substituents. It has a role as an antineoplastic agent, a tyrosine kinase inhibitor, an insulin-like growth factor receptor 1 antagonist and a plant metabolite. It is a lignan, an organic heterotetracyclic compound and a furonaphthodioxole.

Source: ChEBI

Identity
Molecular formulaC22H22O8
Molecular weight414.4 g/mol
IUPAC name(5R,5aR,8aS,9R)-5-hydroxy-9-(3,4,5-trimethoxyphenyl)-5a,6,8a,9-tetrahydro-5H-[2]benzofuro[5,6-f][1,3]benzodioxol-8-one
InChIKeyYJGVMLPVUAXIQN-HAEOHBJNSA-N
SMILESCOC1=CC(=CC(=C1OC)OC)[C@H]2[C@H]3[C@H](COC3=O)[C@H](C4=CC5=C(C=C24)OCO5)O

Computed by PubChem (NCBI)

Synonyms: Picropodophyllin, Picropodophyllotoxin, cyclolignan PPP, picro-podophyllin, Picropodophyllin (PPP), Podophyllotoxin picropodophyllin, (-)PPP, KBioGR_002538, KBio2_007252, PODOPHYLLOTOXIN IMPURITY A [EP IMPURITY]
Related forms of this compound
(5R,5aR,8aS,9R)-5-hydroxy-9-(3,4,5-trimethoxyphenyl)-5a,6,8a,9-tetrahydro-5H-[2]benzofuro[5,6-f][1,3]benzodioxol-8-one C22H22O8
(5R,5aR,8aR,9R)-5-hydroxy-9-(3,4,5-trimethoxyphenyl)-5a,6,8a,9-tetrahydro-5H-[2]benzofuro[5,6-f][1,3]benzodioxol-8-one C22H22O8
(5S,5aR,8aR,9R)-5-hydroxy-9-(3,4,5-trimethoxyphenyl)-5a,6,8a,9-tetrahydro-5H-[2]benzofuro[5,6-f][1,3]benzodioxol-8-one C22H22O8
(5R,5aR,8aS,9R)-9-[3,5-dimethoxy-4-(trideuteriomethoxy)phenyl]-5-hydroxy-5a,6,8a,9-tetrahydro-5H-[2]benzofuro[5,6-f][1,3]benzodioxol-8-one C22H22O8
5-hydroxy-9-(3,4,5-trimethoxyphenyl)-5a,6,8a,9-tetrahydro-5H-[2]benzofuro[5,6-f][1,3]benzodioxol-8-one C22H22O8
(5R,5aR,8aS,9R)-5-hydroxy-9-(3,4,5-trimethoxyphenyl)-5a,6,8a,9-tetrahydro-5H-[2]benzofuro[5,6-f][1,3]benzodioxol-8-one C22H22O8
(5S,5aS,8aR,9R)-5-hydroxy-9-(3,4,5-trimethoxyphenyl)-5a,6,8a,9-tetrahydro-5H-[2]benzofuro[5,6-f][1,3]benzodioxol-8-one C22H22O8
Isomers (same molecular formula)
dimethyl (2S,3S)-2,3-bis[(4-methylbenzoyl)oxy]butanedioate C22H22O8
(5S,5aR,8aR,9R)-9-(4-hydroxy-3,5-dimethoxyphenyl)-5-methoxy-5a,6,8a,9-tetrahydro-5H-[2]benzofuro[5,6-f][1,3]benzodioxol-8-one C22H22O8
5,7-dihydroxy-2-[4-hydroxy-3-(2-hydroxy-3-methylbut-3-enyl)phenyl]-3,6-dimethoxychromen-4-one C22H22O8
(5aR,8aR,9R)-4-hydroxy-9-(3,4,5-trimethoxyphenyl)-5a,6,8a,9-tetrahydro-5H-[2]benzofuro[5,6-f][1,3]benzodioxol-8-one C22H22O8
dimethyl (2R,3R)-2,3-bis[(4-methylbenzoyl)oxy]butanedioate C22H22O8

Also listed as

Picropodophyllotoxin, >95% (HPLC) TRC CAS 477-47-4
Picropodophyllin/ 99.41% (existing batch purity) TargetMol CAS 477-47-4
AXL1717 GLPBio CAS 477-47-4
IGF-1R Inhibitor, PPP Thermo Scientific (Alfa Aesar) CAS 477-47-4
Picropodophyllin Biosynth CAS 477-47-4
Picropodophyllin, 99.85% MedChemExpress CAS 477-47-4
Picropodophyllin (Standard), 99.70% MedChemExpress CAS 477-47-4
Picropodophyllin, 98% Ambeed CAS 477-47-4
(5R,5aS,8aR,9R)-9-Hydroxy-5-(3,4,5-trimethoxyphenyl)-5,8,8a,9-tetrahydrofuro[3',4':6,7]naphtho[2,3-d][1,3]dioxol-6(5aH)-one, 98% BLDpharm CAS 477-47-4
Picropodophyllotoxin >= 96 % HPLC, powde Sigma-Aldrich CAS 477-47-4
IGF-1R Inhibitor, PPP 1PC X 1MG Sigma-Aldrich CAS 477-47-4