Products 477-47-4

CAS 477-47-4 appears in our catalog under these names: Picropodophyllotoxin, Picropodophyllotoxin, >95% (HPLC), Picropodophyllin/ 99.41% (existing batch purity), AXL1717, IGF-1R Inhibitor, PPP . Offered by: Chemat Brand, TRC, TargetMol, GLPBio, Thermo Scientific (Alfa Aesar). Available pack sizes: on request, 100mg, 10mg, 5mg, 25mg, 50mg, 500mg, 250mg.

Picropodophyllotoxin
Chemat Brand, Chemat, Sigma-Aldrich
  • size: on request, 10mg, 1MG, 5MG
  • Variants: 4
from 542.00
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Picropodophyllotoxin, >95% (HPLC)
TRC
  • size: 100mg, 10mg
  • Variants: 2
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Picropodophyllin/ 99.41% (existing batch purity)
TargetMol
  • size: 5mg, 10mg, 25mg, 50mg
  • Variants: 6
from 565.03
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AXL1717
GLPBio
  • size: 10mg, 250mg, 10mM (in 1ml dmso), 50mg
  • Variants: 4
from 718.73
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IGF-1R Inhibitor, PPP
Thermo Scientific (Alfa Aesar)
  • size: 10mg
  • Variants: 1
from 1130.48
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Picropodophyllin
Biosynth
  • size: 0,025g, 0,05g, 0,1g, 0,25g
  • Variants: 5
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Picropodophyllin 98%
Ambeed
  • size: 1mg, 5mg, 10mg, 50mg
  • Variants: 7
from 197.94
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IGF-1R Inhibitor, PPP 1PC X 1MG
Sigma-Aldrich
  • size: 1MG
  • Variants: 1
from 733.00
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Picropodophyllin, 99.85%
MedChemExpress
  • size: 5 mg, 100 mg, 10mM/1mL, 50 mg
  • Variants: 5
from 561.18
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Picropodophyllin (Standard), 99.70%
MedChemExpress
  • size: 25 mg, 5 mg, 50 mg, 10 mg
  • Variants: 5
from 1225.27
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PICROPODOPHYLLIN, 98%
Fluorochem
  • size: 10mg, 50mg
  • Variants: 2
from 820.56
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Structural formula: {0} (CAS {1})

Picropodophyllotoxin is an organic heterotetracyclic compound that has a furonaphthodioxole skeleton bearing 3,4,5-trimethoxyphenyl and hydroxy substituents. It has a role as an antineoplastic agent, a tyrosine kinase inhibitor, an insulin-like growth factor receptor 1 antagonist and a plant metabolite. It is a lignan, an organic heterotetracyclic compound and a furonaphthodioxole.

Source: ChEBI

Identity
Molecular formulaC22H22O8
Molecular weight414.4 g/mol
IUPAC name(5R,5aR,8aS,9R)-5-hydroxy-9-(3,4,5-trimethoxyphenyl)-5a,6,8a,9-tetrahydro-5H-[2]benzofuro[5,6-f][1,3]benzodioxol-8-one
InChIKeyYJGVMLPVUAXIQN-HAEOHBJNSA-N
SMILESCOC1=CC(=CC(=C1OC)OC)[C@H]2[C@H]3[C@H](COC3=O)[C@H](C4=CC5=C(C=C24)OCO5)O

Computed by PubChem (NCBI)

Synonyms: Picropodophyllin, Picropodophyllotoxin, cyclolignan PPP, picro-podophyllin, Picropodophyllin (PPP), Podophyllotoxin picropodophyllin, (-)PPP, KBioGR_002538, KBio2_007252, PODOPHYLLOTOXIN IMPURITY A [EP IMPURITY]
Related forms of this compound
(5R,5aR,8aS,9R)-5-hydroxy-9-(3,4,5-trimethoxyphenyl)-5a,6,8a,9-tetrahydro-5H-[2]benzofuro[5,6-f][1,3]benzodioxol-8-one C22H22O8
(5R,5aR,8aR,9R)-5-hydroxy-9-(3,4,5-trimethoxyphenyl)-5a,6,8a,9-tetrahydro-5H-[2]benzofuro[5,6-f][1,3]benzodioxol-8-one C22H22O8
(5S,5aR,8aR,9R)-5-hydroxy-9-(3,4,5-trimethoxyphenyl)-5a,6,8a,9-tetrahydro-5H-[2]benzofuro[5,6-f][1,3]benzodioxol-8-one C22H22O8
Isomers (same molecular formula)
dimethyl (2S,3S)-2,3-bis[(4-methylbenzoyl)oxy]butanedioate C22H22O8
(5S,5aR,8aR,9R)-9-(4-hydroxy-3,5-dimethoxyphenyl)-5-methoxy-5a,6,8a,9-tetrahydro-5H-[2]benzofuro[5,6-f][1,3]benzodioxol-8-one C22H22O8