Plinabulin (NPI–2358)
cas: 714272-27-2 — see every product listed under this CAS number, including other names
Plinabulin (NPI–2358) (CAS 714272-27-2) is a chemical reagent available from Chemat. Available pack sizes: 10mg, 200mg, 5mg, 50mg. Offered by: GLPBio.
| brand | GLPBio |
|---|---|
| catalog number | GC10235-10 |
| cas | 714272-27-2 |
| size | 10mg |
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Available pack sizes
| brand | size | price | |
|---|---|---|---|
| GLPBio | 10mg | 1238.27 Pln | |
| GLPBio | 200mg | 7346.32 Pln | |
| GLPBio | 5mg | 821.70 Pln | |
| GLPBio | 50mg | 2792.19 Pln |
properties
| purity | No data |
|---|---|
| delivery time | To be confirmed by Chemat |
Plinabulin is a member of the class of 2,5-diketopiperazines that is piperazine-2,5-dione substituted by benzylidene and (5-tert-butyl-1H-imidazol-4-yl)methylidene groups at positions 3 and 6, respectively. It is a vascular disrupting agent and a microtubule destabalising agent which was in clinical trials (now discontinued) for the treatment of non-small cell lung cancer. It has a role as an antineoplastic agent, an angiogenesis inhibitor, a microtubule-destabilising agent and an apoptosis inducer. It is a member of benzenes, a member of imidazoles, a member of 2,5-diketopiperazines and an olefinic compound.
Source: ChEBI
| Molecular formula | C19H20N4O2 |
|---|---|
| Molecular weight | 336.4 g/mol |
| IUPAC name | (3Z,6Z)-3-benzylidene-6-[(5-tert-butyl-1H-imidazol-4-yl)methylidene]piperazine-2,5-dione |
| InChIKey | UNRCMCRRFYFGFX-TYPNBTCFSA-N |
| SMILES | CC(C)(C)C1=C(N=CN1)/C=C\2/C(=O)N/C(=C\C3=CC=CC=C3)/C(=O)N2 |
Computed by PubChem (NCBI)