Ponatinib HCl

cas: 1114544-31-8 — see every product listed under this CAS number, including other names

Ponatinib HCl (CAS 1114544-31-8) is a chemical reagent available from Chemat. Available pack sizes: 2g, 5g, 10g. Offered by: Biosynth.

brandBiosynth
catalog numberFP32437-2g
cas1114544-31-8
size2g

Available pack sizes

brand size price
Biosynth 2g price on request
Biosynth 5g price on request
Biosynth 10g price on request

properties

categoryLife Sciences
purityNo data
delivery time4-6 weeks

Ponatinib hydrochloride is the hydrochloride salt of ponatinib. It is a potent pan inhibitor of tyrosine kinases, active in all single resistance ABL kinase mutations including the T315l mutation. It is approved for the treatment of chronic myeloid leukemia. It has a role as an antineoplastic agent and a tyrosine kinase inhibitor. It contains a ponatinib(1+).

Source: ChEBI

Identity
Molecular formulaC29H28ClF3N6O
Molecular weight569.0 g/mol
IUPAC name3-(2-imidazo[1,2-b]pyridazin-3-ylethynyl)-4-methyl-N-[4-[(4-methylpiperazin-1-yl)methyl]-3-(trifluoromethyl)phenyl]benzamide;hydrochloride
InChIKeyBWTNNZPNKQIADY-UHFFFAOYSA-N
SMILESCC1=C(C=C(C=C1)C(=O)NC2=CC(=C(C=C2)CN3CCN(CC3)C)C(F)(F)F)C#CC4=CN=C5N4N=CC=C5.Cl

Computed by PubChem (NCBI)

Synonyms: Ponatinib hydrochloride, Iclusig, Ponatinib HCl, Ponatinib Mono-hydrochloride, Ponatinib hydrochloride [USAN], Ponatinib (HCl salt), Ponatinib (hydrochloride), C29H28ClF3N6O, 1114544-31-8 (HCl), Iclusig (TN)

Also listed as

3-(2-(Imidazo[1,2-b]pyridazin-3-yl)ethynyl)-4-methyl-n-(4-[(4-methylpiperazin-1-yl)methyl]-3-(trifluoromethyl)phenyl)benzamide hydrochloride, 95% Combi-blocks CAS 1114544-31-8
Ponatinib Hydrochloride, >95% (HPLC) TRC CAS 1114544-31-8
Ponatinib Hydrochloride/ 100% TargetMol CAS 1114544-31-8
Ponatinib (hydrochloride) GLPBio CAS 1114544-31-8
Ponatinib (hydrochloride), 99.76% MedChemExpress CAS 1114544-31-8
Ponatinib (hydrochloride) (Standard) MedChemExpress CAS 1114544-31-8
Ponatinib Hydrochloride, 99%, 99% Chemat CAS 1114544-31-8