Ponatinib (hydrochloride)

cas: 1114544-31-8 — see every product listed under this CAS number, including other names

Ponatinib (hydrochloride) (CAS 1114544-31-8) is a chemical reagent available from Chemat. Available pack sizes: 1g, 100mg, 50mg, 500mg. Offered by: GLPBio.

brandGLPBio
catalog numberGC52104-1
cas1114544-31-8
size1g

Available pack sizes

brand size price
GLPBio 1g 3789.14 Pln
GLPBio 100mg 905.95 Pln
GLPBio 50mg 671.93 Pln
GLPBio 500mg 2487.96 Pln

properties

purityNo data
delivery timeTo be confirmed by Chemat

Ponatinib hydrochloride is the hydrochloride salt of ponatinib. It is a potent pan inhibitor of tyrosine kinases, active in all single resistance ABL kinase mutations including the T315l mutation. It is approved for the treatment of chronic myeloid leukemia. It has a role as an antineoplastic agent and a tyrosine kinase inhibitor. It contains a ponatinib(1+).

Source: ChEBI

Identity
Molecular formulaC29H28ClF3N6O
Molecular weight569.0 g/mol
IUPAC name3-(2-imidazo[1,2-b]pyridazin-3-ylethynyl)-4-methyl-N-[4-[(4-methylpiperazin-1-yl)methyl]-3-(trifluoromethyl)phenyl]benzamide;hydrochloride
InChIKeyBWTNNZPNKQIADY-UHFFFAOYSA-N
SMILESCC1=C(C=C(C=C1)C(=O)NC2=CC(=C(C=C2)CN3CCN(CC3)C)C(F)(F)F)C#CC4=CN=C5N4N=CC=C5.Cl

Computed by PubChem (NCBI)

Synonyms: Ponatinib hydrochloride, Iclusig, Ponatinib HCl, Ponatinib Mono-hydrochloride, Ponatinib hydrochloride [USAN], Ponatinib (HCl salt), Ponatinib (hydrochloride), C29H28ClF3N6O, 1114544-31-8 (HCl), Iclusig (TN)

Also listed as

3-(2-(Imidazo[1,2-b]pyridazin-3-yl)ethynyl)-4-methyl-n-(4-[(4-methylpiperazin-1-yl)methyl]-3-(trifluoromethyl)phenyl)benzamide hydrochloride, 95% Combi-blocks CAS 1114544-31-8
Ponatinib Hydrochloride, >95% (HPLC) TRC CAS 1114544-31-8
Ponatinib Hydrochloride/ 100% TargetMol CAS 1114544-31-8
Ponatinib HCl Biosynth CAS 1114544-31-8
Ponatinib (hydrochloride), 99.76% MedChemExpress CAS 1114544-31-8
Ponatinib (hydrochloride) (Standard) MedChemExpress CAS 1114544-31-8
Ponatinib Hydrochloride, 99%, 99% Chemat CAS 1114544-31-8