RE 201

cas: 254740-64-2 — see every product listed under this CAS number, including other names

RE 201 (CAS 254740-64-2) is a chemical reagent available from Chemat. Available pack sizes: 100mg. Offered by: TRC.

brandTRC
catalog numberTRC-R129300-100MG
cas254740-64-2
size100mg
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purityNo data
delivery timeTo be confirmed by Chemat
Structural formula: {0} (CAS {1})

Sparsentan is a biphenyl that is 1,1'-biphenyl substituted by (4,5-dimethyl-1,2-oxazol-3-yl)aminosulfonyl, ethoxymethyl, and (2-butyl-4-oxo-1,3-diazaspiro[4.4]non-1-en-3-yl)methyl groups at positions 2, 2' and 4', respectively. It is a dual antagonist of endothelin and angiotensin II receptors approved for the reduction of proteinuria in adults with primary immunoglobulin A nephropathy at risk of rapid disease progression. It has a role as an antihypertensive agent, an endothelin A receptor antagonist, an angiotensin receptor antagonist and a nephroprotective agent. It is a member of biphenyls, a sulfonamide, an azaspiro compound, a member of isoxazoles and a benzyl ether.

Source: ChEBI

Identity
Molecular formulaC32H40N4O5S
Molecular weight592.8 g/mol
IUPAC name2-[4-[(2-butyl-4-oxo-1,3-diazaspiro[4.4]non-1-en-3-yl)methyl]-2-(ethoxymethyl)phenyl]-N-(4,5-dimethyl-1,2-oxazol-3-yl)benzenesulfonamide
InChIKeyWRFHGDPIDHPWIQ-UHFFFAOYSA-N
SMILESCCCCC1=NC2(CCCC2)C(=O)N1CC3=CC(=C(C=C3)C4=CC=CC=C4S(=O)(=O)NC5=NOC(=C5C)C)COCC

Computed by PubChem (NCBI)

Synonyms: sparsentan, FILSPARI, esparsentan, sparsentanum, Sparsentan (RE-021), retrophin, Sparsentan [USAN], DARA, Spashentan, Filspari (TN)
Related forms of this compound
2-[4-[(2-butyl-4-oxo-1,3-diazaspiro[4.4]non-1-en-3-yl)methyl]-2-(1,1,2,2,2-pentadeuterioethoxymethyl)phenyl]-N-(4,5-dimethyl-1,2-oxazol-3-yl)benzenesulfonamide C32H40N4O5S

Also listed as

4'-[(2-Butyl-4-oxo-1,3-diazaspiro[4.4]non-1-en-3-yl)methyl]-N-(4,5-dimethyl-3-isoxazolyl)-2'-(ethoxymethyl)[1,1'-biphenyl]-2-sulfonamide, 98%, 98% Chemat CAS 254740-64-2
Sparsentan (RE-021) Chemat Brand CAS 254740-64-2
Sparsentan/ 98.81% (existing batch purity) TargetMol CAS 254740-64-2
Sparsentan (RE–021) GLPBio CAS 254740-64-2
Sparsentan 98% Ambeed CAS 254740-64-2
Sparsentan, 99.87% MedChemExpress CAS 254740-64-2