Sparsentan (RE–021)
cas: 254740-64-2 — see every product listed under this CAS number, including other names
Sparsentan (RE–021) (CAS 254740-64-2) is a chemical reagent available from Chemat. Available pack sizes: 1mg, 10mg, 25mg, 5mg, 10mM (in 1ml dmso), 50mg. Offered by: GLPBio.
| brand | GLPBio |
|---|---|
| catalog number | GC32479-1 |
| cas | 254740-64-2 |
| size | 1mg |
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Available pack sizes
| brand | size | price | |
|---|---|---|---|
| GLPBio | 1mg | 667.25 Pln | |
| GLPBio | 10mg | 1154.02 Pln | |
| GLPBio | 25mg | 1898.22 Pln | |
| GLPBio | 5mg | 877.87 Pln | |
| GLPBio | 10mM (in 1ml dmso) | 1018.28 Pln | |
| GLPBio | 50mg | 2796.87 Pln |
properties
| purity | No data |
|---|---|
| delivery time | To be confirmed by Chemat |
Sparsentan is a biphenyl that is 1,1'-biphenyl substituted by (4,5-dimethyl-1,2-oxazol-3-yl)aminosulfonyl, ethoxymethyl, and (2-butyl-4-oxo-1,3-diazaspiro[4.4]non-1-en-3-yl)methyl groups at positions 2, 2' and 4', respectively. It is a dual antagonist of endothelin and angiotensin II receptors approved for the reduction of proteinuria in adults with primary immunoglobulin A nephropathy at risk of rapid disease progression. It has a role as an antihypertensive agent, an endothelin A receptor antagonist, an angiotensin receptor antagonist and a nephroprotective agent. It is a member of biphenyls, a sulfonamide, an azaspiro compound, a member of isoxazoles and a benzyl ether.
Source: ChEBI
| Molecular formula | C32H40N4O5S |
|---|---|
| Molecular weight | 592.8 g/mol |
| IUPAC name | 2-[4-[(2-butyl-4-oxo-1,3-diazaspiro[4.4]non-1-en-3-yl)methyl]-2-(ethoxymethyl)phenyl]-N-(4,5-dimethyl-1,2-oxazol-3-yl)benzenesulfonamide |
| InChIKey | WRFHGDPIDHPWIQ-UHFFFAOYSA-N |
| SMILES | CCCCC1=NC2(CCCC2)C(=O)N1CC3=CC(=C(C=C3)C4=CC=CC=C4S(=O)(=O)NC5=NOC(=C5C)C)COCC |
Computed by PubChem (NCBI)