cas: 254740-64-2 — see every product listed under this CAS number, including other names
Sparsentan, 99.87% (CAS 254740-64-2) is a chemical reagent available from Chemat. Available pack sizes: 5 mg, 10mM/1mL, 10 mg, 25 mg, 50 mg, 100 mg. Offered by: MedChemExpress.
| brand | MedChemExpress |
|---|---|
| catalog number | HY-17621-5 mg |
| cas | 254740-64-2 |
| size | 5 mg |
| availability | Get quote |
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| brand | size | price | |
|---|---|---|---|
| MedChemExpress | 5 mg | 426.50 Pln | |
| MedChemExpress | 10mM/1mL | 519.38 Pln | |
| MedChemExpress | 10 mg | 612.26 Pln | |
| MedChemExpress | 25 mg | 1118.46 Pln | |
| MedChemExpress | 50 mg | 1694.32 Pln | |
| MedChemExpress | 100 mg | 2428.07 Pln |
| delivery time | over 3 weeks |
|---|---|
| purity | 99.87% |
Sparsentan is a biphenyl that is 1,1'-biphenyl substituted by (4,5-dimethyl-1,2-oxazol-3-yl)aminosulfonyl, ethoxymethyl, and (2-butyl-4-oxo-1,3-diazaspiro[4.4]non-1-en-3-yl)methyl groups at positions 2, 2' and 4', respectively. It is a dual antagonist of endothelin and angiotensin II receptors approved for the reduction of proteinuria in adults with primary immunoglobulin A nephropathy at risk of rapid disease progression. It has a role as an antihypertensive agent, an endothelin A receptor antagonist, an angiotensin receptor antagonist and a nephroprotective agent. It is a member of biphenyls, a sulfonamide, an azaspiro compound, a member of isoxazoles and a benzyl ether.
Source: ChEBI
| Molecular formula | C32H40N4O5S |
|---|---|
| Molecular weight | 592.8 g/mol |
| IUPAC name | 2-[4-[(2-butyl-4-oxo-1,3-diazaspiro[4.4]non-1-en-3-yl)methyl]-2-(ethoxymethyl)phenyl]-N-(4,5-dimethyl-1,2-oxazol-3-yl)benzenesulfonamide |
| InChIKey | WRFHGDPIDHPWIQ-UHFFFAOYSA-N |
| SMILES | CCCCC1=NC2(CCCC2)C(=O)N1CC3=CC(=C(C=C3)C4=CC=CC=C4S(=O)(=O)NC5=NOC(=C5C)C)COCC |
Computed by PubChem (NCBI)