Products 940929-33-9
CAS 940929-33-9 appears in our catalog under these names: SB743921, SB-743921 hydrochloride/ 98%, SB743921 HCl, SB-743921 HCl 99%, SB-743921, 99%, 99%. Offered by: GLPBio, TargetMol, Biosynth, Ambeed, Chemat. Available pack sizes: 10mg, 200mg, 50mg, 1mg, 2mg, 5mg, 25mg, 100mg.
SB-743921 is a chromone that is 4H-chromen-4-one substituted by (1R)-1-[(3-aminopropyl)(4-methylbenzoyl)amino]-2-methylpropyl, benzyl, and chloro groups at positions 2, 3, and 7, respectively. It is a potent inhibitor of kinesin spindle protein (Ki = 0.1 nM) and exhibits antineoplastic activity. It has a role as an antineoplastic agent, a microtubule-destabilising agent and an apoptosis inducer. It is a tertiary carboxamide, a member of benzamides, a member of benzenes, a member of chromones, a member of toluenes, an organochlorine compound and a primary amino compound.
Source: ChEBI
| Molecular formula | C31H33ClN2O3 |
|---|---|
| Molecular weight | 517.1 g/mol |
| IUPAC name | N-(3-aminopropyl)-N-[(1R)-1-(3-benzyl-7-chloro-4-oxochromen-2-yl)-2-methylpropyl]-4-methylbenzamide |
| InChIKey | PGXYIBJJCLWJST-MUUNZHRXSA-N |
| SMILES | CC1=CC=C(C=C1)C(=O)N(CCCN)[C@@H](C2=C(C(=O)C3=C(O2)C=C(C=C3)Cl)CC4=CC=CC=C4)C(C)C |
Computed by PubChem (NCBI)