SM–164

cas: 957135-43-2 — see every product listed under this CAS number, including other names

SM–164 (CAS 957135-43-2) is a chemical reagent available from Chemat. Available pack sizes: 10mg, 200mg, 25mg, 5mg, 10mM (in 1ml dmso). Offered by: GLPBio.

brandGLPBio
catalog numberGC17167-10
cas957135-43-2
size10mg
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Available pack sizes

brand size price
GLPBio 10mg 2038.63 Pln
GLPBio 200mg 13679.04 Pln
GLPBio 25mg 3559.80 Pln
GLPBio 5mg 1542.50 Pln
GLPBio 10mM (in 1ml dmso) 2525.41 Pln

properties

purityNo data
delivery timeTo be confirmed by Chemat
Structural formula: {0} (CAS {1})

SM-164 is a potent cell-permeable and bivalent Smac mimetic which binds to XIAP, cIAP-1 and cIAP-2 proteins (Ki = 0.56 nM, 0.31 nM and 1.1 nM, respectively). It induces apoptosis and tumor regression in cancer xenograft models. It has a role as a radiosensitizing agent, an antineoplastic agent and an apoptosis inducer. It is a secondary carboxamide, a member of benzenes, an organic heterobicyclic compound and a member of triazoles.

Source: ChEBI

Identity
Molecular formulaC62H84N14O6
Molecular weight1121.4 g/mol
IUPAC name(3S,6S,10aS)-N-[(S)-[1-[4-[4-[4-[4-[(S)-[[(3S,6S,10aS)-6-[[(2S)-2-(methylamino)propanoyl]amino]-5-oxo-2,3,6,7,8,9,10,10a-octahydro-1H-pyrrolo[1,2-a]azocine-3-carbonyl]amino]-phenylmethyl]triazol-1-yl]butyl]phenyl]butyl]triazol-4-yl]-phenylmethyl]-6-[[(2S)-2-(methylamino)propanoyl]amino]-5-oxo-2,3,6,7,8,9,10,10a-octahydro-1H-pyrrolo[1,2-a]azocine-3-carboxamide
InChIKeyLGYDZXNSSLRFJS-IOQQVAQYSA-N
SMILESC[C@@H](C(=O)N[C@H]1CCCC[C@H]2CC[C@H](N2C1=O)C(=O)N[C@@H](C3=CC=CC=C3)C4=CN(N=N4)CCCCC5=CC=C(C=C5)CCCCN6C=C(N=N6)[C@H](C7=CC=CC=C7)NC(=O)[C@@H]8CC[C@H]9N8C(=O)[C@H](CCCC9)NC(=O)[C@H](C)NC)NC

Computed by PubChem (NCBI)

Synonyms: orb1219686, orb1309086

Also listed as

Sm-164, 95% Combi-blocks CAS 957135-43-2
SM-164/ 97.25% (existing batch purity) TargetMol CAS 957135-43-2
SM-164 Biosynth CAS 957135-43-2
SM-164 98% Ambeed CAS 957135-43-2
(3S,3'S,6S,6'S,10aS,10a'S)-N,N'-((1S,1'S)-((1,4-Phenylenebis(butane-4,1-diyl))bis(1H-1,2,3-triazole-1,4-diyl))bis(phenylmethylene))bis(6-((S)-2-(methylamino)propanamido)-5-oxodecahydropyrrolo[1,2-a]azocine-3-carboxamide), 98%, 98% Chemat CAS 957135-43-2
SM-164, 99.49% MedChemExpress CAS 957135-43-2