SM-164, 99.49%

cas: 957135-43-2 — see every product listed under this CAS number, including other names

SM-164, 99.49% (CAS 957135-43-2) is a chemical reagent available from Chemat. Available pack sizes: 10mM/1mL, 100 mg, 5 mg, 10 mg, 50 mg. Offered by: MedChemExpress.

brand	MedChemExpress
catalog number	HY-15989-10mM/1mL
cas	957135-43-2
size	10mM/1mL
availability	In stock

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Available pack sizes

brand	size	price
MedChemExpress	10mM/1mL	3668.02 Pln
MedChemExpress	100 mg	12208.33 Pln
MedChemExpress	5 mg	1801.13 Pln
MedChemExpress	10 mg	2999.28 Pln
MedChemExpress	50 mg	8757.84 Pln

properties

delivery time	1-2 weeks
purity	99.49%

SM-164 is a potent cell-permeable and bivalent Smac mimetic which binds to XIAP, cIAP-1 and cIAP-2 proteins (Ki = 0.56 nM, 0.31 nM and 1.1 nM, respectively). It induces apoptosis and tumor regression in cancer xenograft models. It has a role as a radiosensitizing agent, an antineoplastic agent and an apoptosis inducer. It is a secondary carboxamide, a member of benzenes, an organic heterobicyclic compound and a member of triazoles.

Source: ChEBI

Identity
Molecular formula	C₆₂H₈₄N₁₄O₆
Molecular weight	1121.4 g/mol
IUPAC name	(3S,6S,10aS)-N-[(S)-[1-[4-[4-[4-[4-[(S)-[[(3S,6S,10aS)-6-[[(2S)-2-(methylamino)propanoyl]amino]-5-oxo-2,3,6,7,8,9,10,10a-octahydro-1H-pyrrolo[1,2-a]azocine-3-carbonyl]amino]-phenylmethyl]triazol-1-yl]butyl]phenyl]butyl]triazol-4-yl]-phenylmethyl]-6-[[(2S)-2-(methylamino)propanoyl]amino]-5-oxo-2,3,6,7,8,9,10,10a-octahydro-1H-pyrrolo[1,2-a]azocine-3-carboxamide
InChIKey	LGYDZXNSSLRFJS-IOQQVAQYSA-N
SMILES	C[C@@H](C(=O)N[C@H]1CCCC[C@H]2CC[C@H](N2C1=O)C(=O)N[C@@H](C3=CC=CC=C3)C4=CN(N=N4)CCCCC5=CC=C(C=C5)CCCCN6C=C(N=N6)[C@H](C7=CC=CC=C7)NC(=O)[C@@H]8CC[C@H]9N8C(=O)[C@H](CCCC9)NC(=O)[C@H](C)NC)NC