Sm-164, 95%

cas: 957135-43-2 — see every product listed under this CAS number, including other names

Sm-164, 95% (CAS 957135-43-2) is a chemical reagent available from Chemat. Available pack sizes: 100mg. Offered by: Combi-blocks.

brandCombi-blocks
catalog numberHE-3194-100mg
cas957135-43-2
size100mg
Documents: Safety Data Sheet (MSDS)
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Available pack sizes

brand size price
Combi-blocks 100mg price on request

properties

purity95%
delivery time1-2 weeks (only if in stock, to check click on availability)
Structural formula: {0} (CAS {1})

SM-164 is a potent cell-permeable and bivalent Smac mimetic which binds to XIAP, cIAP-1 and cIAP-2 proteins (Ki = 0.56 nM, 0.31 nM and 1.1 nM, respectively). It induces apoptosis and tumor regression in cancer xenograft models. It has a role as a radiosensitizing agent, an antineoplastic agent and an apoptosis inducer. It is a secondary carboxamide, a member of benzenes, an organic heterobicyclic compound and a member of triazoles.

Source: ChEBI

Identity
Molecular formulaC62H84N14O6
Molecular weight1121.4 g/mol
IUPAC name(3S,6S,10aS)-N-[(S)-[1-[4-[4-[4-[4-[(S)-[[(3S,6S,10aS)-6-[[(2S)-2-(methylamino)propanoyl]amino]-5-oxo-2,3,6,7,8,9,10,10a-octahydro-1H-pyrrolo[1,2-a]azocine-3-carbonyl]amino]-phenylmethyl]triazol-1-yl]butyl]phenyl]butyl]triazol-4-yl]-phenylmethyl]-6-[[(2S)-2-(methylamino)propanoyl]amino]-5-oxo-2,3,6,7,8,9,10,10a-octahydro-1H-pyrrolo[1,2-a]azocine-3-carboxamide
InChIKeyLGYDZXNSSLRFJS-IOQQVAQYSA-N
SMILESC[C@@H](C(=O)N[C@H]1CCCC[C@H]2CC[C@H](N2C1=O)C(=O)N[C@@H](C3=CC=CC=C3)C4=CN(N=N4)CCCCC5=CC=C(C=C5)CCCCN6C=C(N=N6)[C@H](C7=CC=CC=C7)NC(=O)[C@@H]8CC[C@H]9N8C(=O)[C@H](CCCC9)NC(=O)[C@H](C)NC)NC

Computed by PubChem (NCBI)

Synonyms: orb1219686, orb1309086

Also listed as

SM-164/ 97.25% (existing batch purity) TargetMol CAS 957135-43-2
SM–164 GLPBio CAS 957135-43-2
SM-164 Biosynth CAS 957135-43-2
SM-164 98% Ambeed CAS 957135-43-2
(3S,3'S,6S,6'S,10aS,10a'S)-N,N'-((1S,1'S)-((1,4-Phenylenebis(butane-4,1-diyl))bis(1H-1,2,3-triazole-1,4-diyl))bis(phenylmethylene))bis(6-((S)-2-(methylamino)propanamido)-5-oxodecahydropyrrolo[1,2-a]azocine-3-carboxamide), 98%, 98% Chemat CAS 957135-43-2
SM-164, 99.49% MedChemExpress CAS 957135-43-2