TAK-632, 99.02%
cas: 1228591-30-7 — see every product listed under this CAS number, including other names
TAK-632, 99.02% (CAS 1228591-30-7) is a chemical reagent available from Chemat. Available pack sizes: 10 mg, 5 mg, 100 mg, 10mM/1mL, 25 mg, 50 mg. Offered by: MedChemExpress.
| brand | MedChemExpress |
|---|---|
| catalog number | HY-15767-10 mg |
| cas | 1228591-30-7 |
| size | 10 mg |
| availability | In stock |
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Available pack sizes
| brand | size | price | |
|---|---|---|---|
| MedChemExpress | 10 mg | 542.60 Pln | |
| MedChemExpress | 5 mg | 384.71 Pln | |
| MedChemExpress | 100 mg | 2423.42 Pln | |
| MedChemExpress | 10mM/1mL | 440.44 Pln | |
| MedChemExpress | 25 mg | 1007.00 Pln | |
| MedChemExpress | 50 mg | 1559.64 Pln |
properties
| delivery time | 1-2 weeks |
|---|---|
| purity | 99.02% |
TAK-632 is a member of the class of benzothiazoles that is 1,3-benzothiazole substituted by (cyclopropanecarbonyl)amino, 4-fluoro-3-{2-[3-(trifluoromethyl)phenyl]acetamido}phenoxy, and cyano groups at positions 2, 6 and 7, respectively. It is a potent pan-RAF inhibitor with IC50 of 1.4, 2.4 and 8.3 nM for CRAF, BRAFV600E, BRAFWT, respectively. It has a role as a necroptosis inhibitor, an antineoplastic agent, an apoptosis inducer, a B-Raf inhibitor and an EC 2.7.11.26 (tau-protein kinase) inhibitor. It is a secondary carboxamide, a nitrile, an aromatic ether, a member of benzothiazoles, a cyclopropylcarboxamide, a member of (trifluoromethyl)benzenes and a member of monofluorobenzenes.
Source: ChEBI
| Molecular formula | C27H18F4N4O3S |
|---|---|
| Molecular weight | 554.5 g/mol |
| IUPAC name | N-[7-cyano-6-[4-fluoro-3-[[2-[3-(trifluoromethyl)phenyl]acetyl]amino]phenoxy]-1,3-benzothiazol-2-yl]cyclopropanecarboxamide |
| InChIKey | OJFKUJDRGJSAQB-UHFFFAOYSA-N |
| SMILES | C1CC1C(=O)NC2=NC3=C(S2)C(=C(C=C3)OC4=CC(=C(C=C4)F)NC(=O)CC5=CC(=CC=C5)C(F)(F)F)C#N |
Computed by PubChem (NCBI)