THZ1, 99.84%
cas: 1604810-83-4 — see every product listed under this CAS number, including other names
THZ1, 99.84% (CAS 1604810-83-4) is a chemical reagent available from Chemat. Available pack sizes: 25 mg, 50 mg, 5 mg, 100 mg, 10 mg, 10mM/1mL. Offered by: MedChemExpress.
| brand | MedChemExpress |
|---|---|
| catalog number | HY-80013-25 mg |
| cas | 1604810-83-4 |
| size | 25 mg |
| availability | In stock |
Need more information?
Ask us about this product — we're happy to help.
Available pack sizes
| brand | size | price | |
|---|---|---|---|
| MedChemExpress | 25 mg | 1801.13 Pln | |
| MedChemExpress | 50 mg | 2493.08 Pln | |
| MedChemExpress | 5 mg | 630.84 Pln | |
| MedChemExpress | 100 mg | 4076.69 Pln | |
| MedChemExpress | 10 mg | 1007.00 Pln | |
| MedChemExpress | 10mM/1mL | 751.58 Pln |
properties
| delivery time | 1-2 weeks |
|---|---|
| purity | 99.84% |
THZ1 is a member of the class of indoles that is 1H-indole substituted by a 5-chloro-2-[3-(4-{[(2E)-4-(dimethylamino)but-2-enoyl]amino}benzamido)anilino]pyrimidin-4-yl group at position 3. It is a selective and potent covalent inhibitor of CDK7 that exhibits anti-proliferative effects in cancer cell lines. It has a role as an antineoplastic agent and an EC 2.7.11.22 (cyclin-dependent kinase) inhibitor. It is a secondary carboxamide, a member of benzamides, a member of indoles, an organochlorine compound, an aminopyrimidine and an enamide.
Source: ChEBI
| Molecular formula | C31H28ClN7O2 |
|---|---|
| Molecular weight | 566.1 g/mol |
| IUPAC name | N-[3-[[5-chloro-4-(1H-indol-3-yl)pyrimidin-2-yl]amino]phenyl]-4-[[(E)-4-(dimethylamino)but-2-enoyl]amino]benzamide |
| InChIKey | OBJNFLYHUXWUPF-IZZDOVSWSA-N |
| SMILES | CN(C)C/C=C/C(=O)NC1=CC=C(C=C1)C(=O)NC2=CC=CC(=C2)NC3=NC=C(C(=N3)C4=CNC5=CC=CC=C54)Cl |
Computed by PubChem (NCBI)
Synonyms:
orb1303940