THZ1 Hydrochloride
cas: 1604810-83-4 — see every product listed under this CAS number, including other names
THZ1 Hydrochloride (CAS 1604810-83-4) is a chemical reagent available from Chemat. Available pack sizes: 10mg, 25mg, 5mg, 10mM (in 1ml dmso). Offered by: GLPBio.
| brand | GLPBio |
|---|---|
| catalog number | GC12642-10 |
| cas | 1604810-83-4 |
| size | 10mg |
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Available pack sizes
| brand | size | price | |
|---|---|---|---|
| GLPBio | 10mg | 929.36 Pln | |
| GLPBio | 25mg | 1500.38 Pln | |
| GLPBio | 5mg | 681.29 Pln | |
| GLPBio | 10mM (in 1ml dmso) | 765.54 Pln |
properties
| purity | No data |
|---|---|
| delivery time | To be confirmed by Chemat |
THZ1 is a member of the class of indoles that is 1H-indole substituted by a 5-chloro-2-[3-(4-{[(2E)-4-(dimethylamino)but-2-enoyl]amino}benzamido)anilino]pyrimidin-4-yl group at position 3. It is a selective and potent covalent inhibitor of CDK7 that exhibits anti-proliferative effects in cancer cell lines. It has a role as an antineoplastic agent and an EC 2.7.11.22 (cyclin-dependent kinase) inhibitor. It is a secondary carboxamide, a member of benzamides, a member of indoles, an organochlorine compound, an aminopyrimidine and an enamide.
Source: ChEBI
| Molecular formula | C31H28ClN7O2 |
|---|---|
| Molecular weight | 566.1 g/mol |
| IUPAC name | N-[3-[[5-chloro-4-(1H-indol-3-yl)pyrimidin-2-yl]amino]phenyl]-4-[[(E)-4-(dimethylamino)but-2-enoyl]amino]benzamide |
| InChIKey | OBJNFLYHUXWUPF-IZZDOVSWSA-N |
| SMILES | CN(C)C/C=C/C(=O)NC1=CC=C(C=C1)C(=O)NC2=CC=CC(=C2)NC3=NC=C(C(=N3)C4=CNC5=CC=CC=C54)Cl |
Computed by PubChem (NCBI)
Synonyms:
orb1303940