THZ1

cas: 1604810-83-4 — see every product listed under this CAS number, including other names

THZ1 (CAS 1604810-83-4) is a chemical reagent available from Chemat. Available pack sizes: 25mg, 10mg, 5mg, 10mM (in 1ml dmso), 50mg, 100mg. Offered by: TRC, GLPBio, Biosynth.

brandTRC
catalog numberTRC-T430000-25MG
cas1604810-83-4
size25mg
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Available pack sizes

brand size price
TRC 25mg price on request
GLPBio 10mg 891.91 Pln
GLPBio 25mg 1439.53 Pln
GLPBio 5mg 695.33 Pln
GLPBio 10mM (in 1ml dmso) 737.45 Pln
Biosynth 50mg price on request
Biosynth 25mg price on request
Biosynth 100mg price on request

properties

purityNo data
delivery timeTo be confirmed by Chemat
Structural formula: {0} (CAS {1})

THZ1 is a member of the class of indoles that is 1H-indole substituted by a 5-chloro-2-[3-(4-{[(2E)-4-(dimethylamino)but-2-enoyl]amino}benzamido)anilino]pyrimidin-4-yl group at position 3. It is a selective and potent covalent inhibitor of CDK7 that exhibits anti-proliferative effects in cancer cell lines. It has a role as an antineoplastic agent and an EC 2.7.11.22 (cyclin-dependent kinase) inhibitor. It is a secondary carboxamide, a member of benzamides, a member of indoles, an organochlorine compound, an aminopyrimidine and an enamide.

Source: ChEBI

Identity
Molecular formulaC31H28ClN7O2
Molecular weight566.1 g/mol
IUPAC nameN-[3-[[5-chloro-4-(1H-indol-3-yl)pyrimidin-2-yl]amino]phenyl]-4-[[(E)-4-(dimethylamino)but-2-enoyl]amino]benzamide
InChIKeyOBJNFLYHUXWUPF-IZZDOVSWSA-N
SMILESCN(C)C/C=C/C(=O)NC1=CC=C(C=C1)C(=O)NC2=CC=CC(=C2)NC3=NC=C(C(=N3)C4=CNC5=CC=CC=C54)Cl

Computed by PubChem (NCBI)

Synonyms: orb1303940

Also listed as

Benzamide, N-[3-[[5-chloro-4-(1H-indol-3-yl)-2-pyrimidinyl]amino]phenyl]-4-[[(2E)-4-(dimethylamino)-1-oxo-2-buten-1-yl]amino]-, 98% Fluorochem CAS 1604810-83-4
N-[3-[[5-Chloro-4-(1H-indol-3-yl)-2-pyrimidinyl]amino]phenyl]-4-[[(2E)-4-(dimethylamino)-1-oxo-2-buten-1-yl]amino]benzamide, 99.12% ,, 99.12% , Chemat CAS 1604810-83-4
THZ1/ 99.12% (existing batch purity) TargetMol CAS 1604810-83-4
THZ1 Hydrochloride GLPBio CAS 1604810-83-4
THZ1, 99.84% MedChemExpress CAS 1604810-83-4