Products 112522-64-2
CAS 112522-64-2 appears in our catalog under these names: 4-(Acetylamino)-N-(2-aminophenyl)benzamide, 98%, 98%, Tacedinaline, Tacedinaline/ 99.12% (existing batch purity), CI994 (Tacedinaline), Acetyldinaline, >98.0%(HPLC). Offered by: Chemat, TRC, TargetMol, GLPBio, TCI. Available pack sizes: 10mg, 50mg, 100mg, 250mg, 1g, 1mg, 500mg, 200mg.
Tacedinaline is a benzamide obtained by formal condensation of the carboxy group of 4-acetamidobenzoic acid with one of the amino groups of 1,2-phenylenediamine. An oral cytostatic drug with impressive differential activity against leukemic cells and normal stem-cells. Also used in combination therapy for selected tumors including non-smoll cell lung, pancreatic, breast, and colorectal cancers. It has a role as an antineoplastic agent and an EC 3.5.1.98 (histone deacetylase) inhibitor. It is a member of acetamides, a member of benzamides and a substituted aniline. It is functionally related to a 1,2-phenylenediamine.
Source: ChEBI
| Molecular formula | C15H15N3O2 |
|---|---|
| Molecular weight | 269.30 g/mol |
| IUPAC name | 4-acetamido-N-(2-aminophenyl)benzamide |
| InChIKey | VAZAPHZUAVEOMC-UHFFFAOYSA-N |
| SMILES | CC(=O)NC1=CC=C(C=C1)C(=O)NC2=CC=CC=C2N |
Computed by PubChem (NCBI)