Tesevatinib (XL–647)

cas: 781613-23-8 — see every product listed under this CAS number, including other names

Tesevatinib (XL–647) (CAS 781613-23-8) is a chemical reagent available from Chemat. Available pack sizes: 10mg, 10mM (in 1ml dmso), 2mg, 5mg. Offered by: GLPBio.

brandGLPBio
catalog numberGC31752-10
cas781613-23-8
size10mg
Need more information?

Ask us about this product — we're happy to help.

Available pack sizes

brand size price
GLPBio 10mg 2436.48 Pln
GLPBio 10mM (in 1ml dmso) 1608.03 Pln
GLPBio 2mg 1004.24 Pln
GLPBio 5mg 1706.32 Pln

properties

purityNo data
delivery timeTo be confirmed by Chemat
Structural formula: {0} (CAS {1})

Tesevatinib is a member of the class of quinazolines that is quinazoline substituted by (3,4-dichloro-2-fluorophenyl)amino, methoxy, and [(3aR,5r,6aS)-2-methyloctahydrocyclopenta[c]pyrrol-5-yl]methoxy groups at positions 4, 6 and 7, respectively. It is a multi-target tyrosine kinase inhibitor of EGFR, ErbB2, KDR, Flt4 and EphB4 and exhibits anti-cancer properties. It has a role as an antineoplastic agent, an EC 2.7.10.1 (receptor protein-tyrosine kinase) inhibitor and an epidermal growth factor receptor antagonist. It is a dichlorobenzene, an aromatic ether, a member of quinazolines, a diether, a secondary amino compound, a tertiary amino compound and a member of monofluorobenzenes.

Source: ChEBI

Identity
Molecular formulaC24H25Cl2FN4O2
Molecular weight491.4 g/mol
IUPAC name7-[[(3aS,6aR)-2-methyl-3,3a,4,5,6,6a-hexahydro-1H-cyclopenta[c]pyrrol-5-yl]methoxy]-N-(3,4-dichloro-2-fluorophenyl)-6-methoxyquinazolin-4-amine
InChIKeyHVXKQKFEHMGHSL-GOOCMWNKSA-N
SMILESCN1C[C@H]2CC(C[C@H]2C1)COC3=C(C=C4C(=C3)N=CN=C4NC5=C(C(=C(C=C5)Cl)Cl)F)OC

Computed by PubChem (NCBI)

Synonyms: Tesevatinib, TESEVATINIB [USAN], Tesevatinib [USAN:INN], tesevatinibum, C24H25Cl2FN4O2, TESEVATINIB [INN], Tesevatinib (USAN/INN), TESEVATINIB [WHO-DD], orb1296161
Related forms of this compound
7-[[(3aS,6aR)-2-methyl-3,3a,4,5,6,6a-hexahydro-1H-cyclopenta[c]pyrrol-5-yl]methoxy]-N-(3,4-dichloro-2-fluorophenyl)-6-methoxyquinazolin-4-amine C24H25Cl2FN4O2

Also listed as

Tesevatinib, 98% AmBeed CAS 781613-23-8
Tesevatinib/ 97.89% (existing batch purity) TargetMol CAS 781613-23-8
XL 647 Biosynth CAS 781613-23-8
Tesevatinib, 99.41% MedChemExpress CAS 781613-23-8
Tesevatinib (Standard) MedChemExpress CAS 781613-23-8
Tesevatinib, 99% Ambeed CAS 781613-23-8
N-(3,4-Dichloro-2-fluorophenyl)-6-methoxy-7-(((3aR,5r,6aS)-2-methyloctahydrocyclopenta[c]pyrrol-5-yl)methoxy)quinazolin-4-amine, 99% BLDpharm CAS 781613-23-8
N-(3,4-dichloro-2-fluorophenyl)-6-methoxy-7-(((3aR,6aS)-2-methyloctahydrocyclopenta[c]pyrrol-5-yl)methoxy)quinazolin-4-amine, 99% Chemat CAS 781613-23-8