Products 781613-23-8
CAS 781613-23-8 appears in our catalog under these names: Tesevatinib, 98%, Tesevatinib/ 97.89% (existing batch purity), Tesevatinib (XL–647), XL 647, Tesevatinib 99%. Offered by: AmBeed, TargetMol, GLPBio, Biosynth, Chemat. Available pack sizes: 250mg, 1mg, 2mg, 5mg, 10mg, 25mg, 50mg, 10mM (in 1ml dmso).
Tesevatinib is a member of the class of quinazolines that is quinazoline substituted by (3,4-dichloro-2-fluorophenyl)amino, methoxy, and [(3aR,5r,6aS)-2-methyloctahydrocyclopenta[c]pyrrol-5-yl]methoxy groups at positions 4, 6 and 7, respectively. It is a multi-target tyrosine kinase inhibitor of EGFR, ErbB2, KDR, Flt4 and EphB4 and exhibits anti-cancer properties. It has a role as an antineoplastic agent, an EC 2.7.10.1 (receptor protein-tyrosine kinase) inhibitor and an epidermal growth factor receptor antagonist. It is a dichlorobenzene, an aromatic ether, a member of quinazolines, a diether, a secondary amino compound, a tertiary amino compound and a member of monofluorobenzenes.
Source: ChEBI
| Molecular formula | C24H25Cl2FN4O2 |
|---|---|
| Molecular weight | 491.4 g/mol |
| IUPAC name | 7-[[(3aS,6aR)-2-methyl-3,3a,4,5,6,6a-hexahydro-1H-cyclopenta[c]pyrrol-5-yl]methoxy]-N-(3,4-dichloro-2-fluorophenyl)-6-methoxyquinazolin-4-amine |
| InChIKey | HVXKQKFEHMGHSL-GOOCMWNKSA-N |
| SMILES | CN1C[C@H]2CC(C[C@H]2C1)COC3=C(C=C4C(=C3)N=CN=C4NC5=C(C(=C(C=C5)Cl)Cl)F)OC |
Computed by PubChem (NCBI)