N-(3,4-dichloro-2-fluorophenyl)-6-methoxy-7-(((3aR,6aS)-2-methyloctahydrocyclopenta[c]pyrrol-5-yl)methoxy)quinazolin-4-amine, 99%

cas: 781613-23-8 — see every product listed under this CAS number, including other names

N-(3,4-dichloro-2-fluorophenyl)-6-methoxy-7-(((3aR,6aS)-2-methyloctahydrocyclopenta[c]pyrrol-5-yl)methoxy)quinazolin-4-amine, 99% (CAS 781613-23-8) is a chemical reagent available from Chemat. Available pack sizes: 5mg, 10mg, 25mg, 50mg, 100mg. Offered by: Chemat.

brandChemat
catalog numberCh11G4QJ-5mg
cas781613-23-8
size5mg
availability 0.5g
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Available pack sizes

brand size price
Chemat 5mg 846.80 Pln
Chemat 10mg 1398.80 Pln
Chemat 25mg 2733.20 Pln
Chemat 50mg 4600.40 Pln
Chemat 100mg 7778.00 Pln

properties

purity99%
delivery time3 weeks
Structural formula: {0} (CAS {1})

Tesevatinib is a member of the class of quinazolines that is quinazoline substituted by (3,4-dichloro-2-fluorophenyl)amino, methoxy, and [(3aR,5r,6aS)-2-methyloctahydrocyclopenta[c]pyrrol-5-yl]methoxy groups at positions 4, 6 and 7, respectively. It is a multi-target tyrosine kinase inhibitor of EGFR, ErbB2, KDR, Flt4 and EphB4 and exhibits anti-cancer properties. It has a role as an antineoplastic agent, an EC 2.7.10.1 (receptor protein-tyrosine kinase) inhibitor and an epidermal growth factor receptor antagonist. It is a dichlorobenzene, an aromatic ether, a member of quinazolines, a diether, a secondary amino compound, a tertiary amino compound and a member of monofluorobenzenes.

Source: ChEBI

Identity
Molecular formulaC24H25Cl2FN4O2
Molecular weight491.4 g/mol
IUPAC name7-[[(3aS,6aR)-2-methyl-3,3a,4,5,6,6a-hexahydro-1H-cyclopenta[c]pyrrol-5-yl]methoxy]-N-(3,4-dichloro-2-fluorophenyl)-6-methoxyquinazolin-4-amine
InChIKeyHVXKQKFEHMGHSL-GOOCMWNKSA-N
SMILESCN1C[C@H]2CC(C[C@H]2C1)COC3=C(C=C4C(=C3)N=CN=C4NC5=C(C(=C(C=C5)Cl)Cl)F)OC

Computed by PubChem (NCBI)

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