cas: 1351636-18-4 — see every product listed under this CAS number, including other names
Tirabrutinib, 98+% (CAS 1351636-18-4) is a chemical reagent available from Chemat. Available pack sizes: 1mg, 5mg. Offered by: Fluorochem.
| brand | Fluorochem |
|---|---|
| catalog number | F979696-1MG |
| cas | 1351636-18-4 |
| size | 1mg |
| availability | In Stock China |
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| brand | size | price | |
|---|---|---|---|
| Fluorochem | 1mg | 232.23 Pln | |
| Fluorochem | 5mg | 305.12 Pln |
| purity | 98+% |
|---|---|
| dual use | No |
| currency | EUR |
| delivery time | 3-4 weeks |
| category | Odczynniki chemiczne |
Tirabrutinib is an orally available formulation containing an inhibitor of Bruton agammaglobulinemia tyrosine kinase (BTK), with potential antineoplastic activity. Upon administration, tirabrutinib covalently binds to BTK within B cells, thereby preventing B cell receptor signaling and impeding B cell development. As a result, this agent may inhibit the proliferation of B cell malignancies.
Source: ChEBI
| Molecular formula | C25H22N6O3 |
|---|---|
| Molecular weight | 454.5 g/mol |
| IUPAC name | 6-amino-9-[(3R)-1-but-2-ynoylpyrrolidin-3-yl]-7-(4-phenoxyphenyl)purin-8-one |
| InChIKey | SEJLPXCPMNSRAM-GOSISDBHSA-N |
| SMILES | CC#CC(=O)N1CC[C@H](C1)N2C3=NC=NC(=C3N(C2=O)C4=CC=C(C=C4)OC5=CC=CC=C5)N |
Computed by PubChem (NCBI)