cas: 871700-17-3 — see every product listed under this CAS number, including other names
Trametinib (GSK1120212) (CAS 871700-17-3) is a chemical reagent available from Chemat. Available pack sizes: 200mg, 10mM (in 1ml dmso), 50mg, 500mg. Offered by: GLPBio.
| brand | GLPBio |
|---|---|
| catalog number | GC13508-200 |
| cas | 871700-17-3 |
| size | 200mg |
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| brand | size | price | |
|---|---|---|---|
| GLPBio | 200mg | 1051.05 Pln | |
| GLPBio | 10mM (in 1ml dmso) | 611.08 Pln | |
| GLPBio | 50mg | 728.09 Pln | |
| GLPBio | 500mg | 1767.16 Pln |
| purity | No data |
|---|---|
| delivery time | To be confirmed by Chemat |
Trametinib is a pyridopyrimidine that is used (as its dimethyl sulfoxide addition compound) for the treatment of patients with unresectable or metastatic melanoma with BRAF V600E or V600K mutations, and who have not received prior BRAF inhibitor treatment. It has a role as an anticoronaviral agent, a geroprotector, an antineoplastic agent and an EC 2.7.11.24 (mitogen-activated protein kinase) inhibitor. It is a member of acetamides, an aromatic amine, a ring assembly, an organoiodine compound, an organofluorine compound, a pyridopyrimidine and a member of cyclopropanes.
Source: ChEBI
| Molecular formula | C26H23FIN5O4 |
|---|---|
| Molecular weight | 615.4 g/mol |
| IUPAC name | N-[3-[3-cyclopropyl-5-(2-fluoro-4-iodoanilino)-6,8-dimethyl-2,4,7-trioxopyrido[4,3-d]pyrimidin-1-yl]phenyl]acetamide |
| InChIKey | LIRYPHYGHXZJBZ-UHFFFAOYSA-N |
| SMILES | CC1=C2C(=C(N(C1=O)C)NC3=C(C=C(C=C3)I)F)C(=O)N(C(=O)N2C4=CC=CC(=C4)NC(=O)C)C5CC5 |
Computed by PubChem (NCBI)