Trametinib

cas: 871700-17-3 — see every product listed under this CAS number, including other names

Trametinib (CAS 871700-17-3) is a chemical reagent available from Chemat. Available pack sizes: on request, 0,5g, 0,25g, 1g, 2g. Offered by: Chemat Brand, Biosynth.

brandChemat Brand
catalog numberULT122001
cas871700-17-3
sizeon request
availability Do potwierdzenia przez Chemat|To be confirmed by Chemat
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Available pack sizes

brand size price
Chemat Brand on request price on request
Biosynth 0,5g price on request
Biosynth 0,25g price on request
Biosynth 1g price on request
Biosynth 2g price on request

properties

purityNo data
categoryChemicals
delivery timeTo be confirmed by Chemat

Trametinib is a pyridopyrimidine that is used (as its dimethyl sulfoxide addition compound) for the treatment of patients with unresectable or metastatic melanoma with BRAF V600E or V600K mutations, and who have not received prior BRAF inhibitor treatment. It has a role as an anticoronaviral agent, a geroprotector, an antineoplastic agent and an EC 2.7.11.24 (mitogen-activated protein kinase) inhibitor. It is a member of acetamides, an aromatic amine, a ring assembly, an organoiodine compound, an organofluorine compound, a pyridopyrimidine and a member of cyclopropanes.

Source: ChEBI

Identity
Molecular formulaC26H23FIN5O4
Molecular weight615.4 g/mol
IUPAC nameN-[3-[3-cyclopropyl-5-(2-fluoro-4-iodoanilino)-6,8-dimethyl-2,4,7-trioxopyrido[4,3-d]pyrimidin-1-yl]phenyl]acetamide
InChIKeyLIRYPHYGHXZJBZ-UHFFFAOYSA-N
SMILESCC1=C2C(=C(N(C1=O)C)NC3=C(C=C(C=C3)I)F)C(=O)N(C(=O)N2C4=CC=CC(=C4)NC(=O)C)C5CC5

Computed by PubChem (NCBI)

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