Products 178606-66-1
CAS 178606-66-1 appears in our catalog under these names: U-104/ 99.6% (existing batch purity), U–104, U-104, >98.0%(HPLC)(qNMR), U-104 98%, Carbonic Anhydrase IX/XII In 1PC X 5MG. Offered by: TargetMol, GLPBio, TCI, Ambeed, Sigma-Aldrich. Available pack sizes: 5mg, 10mg, 25mg, 50mg, 100mg, 200mg, 500mg, 10mM (in 1ml dmso).
SLC-0111 is it is a potent carbonic anhydrase inhibitor (Ki = 45.1 nM and 4.5 nM for CA IX and CA XII, respectively) that is in clinical trials for the treatment of hypoxic malignancies. It has a role as an EC 4.2.1.1 (carbonic anhydrase) inhibitor and an antineoplastic agent. It is a member of phenylureas, a sulfonamide and a member of monofluorobenzenes.
Source: ChEBI
| Molecular formula | C13H12FN3O3S |
|---|---|
| Molecular weight | 309.32 g/mol |
| IUPAC name | 1-(4-fluorophenyl)-3-(4-sulfamoylphenyl)urea |
| InChIKey | YJQZNWPYLCNRLP-UHFFFAOYSA-N |
| SMILES | C1=CC(=CC=C1NC(=O)NC2=CC=C(C=C2)S(=O)(=O)N)F |
Computed by PubChem (NCBI)
Synonyms:
1-(4-fluorophenyl)-3-(4-sulfamoylphenyl)urea, CAIX Inhibitor SLC-0111, 4-(3-(4-fluorophenyl)ureido)benzenesulfonamide, 4-{[(4-Fluorophenyl)carbamoyl]amino}benzenesulfonamide, mst-104, 3n4b, 4-[3-(4-Fluorophenyl)ureido]benzenesulfonamide, Carbonic Anhydrase IX/XII Inhibitor II(U-104), 4-{[(4'-Fluorophenyl)Carbamoyl]Amino}Benzenesulfonamide, 4-(((4-Fluoroanilino)carbonyl)amino)benzenesulfonamide