Vamorolone
cas: 13209-41-1 — see every product listed under this CAS number, including other names
Vamorolone (CAS 13209-41-1) is a chemical reagent available from Chemat. Available pack sizes: 1mg, 10mg, 5mg, 10mM (in 1ml dmso), 50mg. Offered by: GLPBio.
| brand | GLPBio |
|---|---|
| catalog number | GC39564-1 |
| cas | 13209-41-1 |
| size | 1mg |
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Available pack sizes
| brand | size | price | |
|---|---|---|---|
| GLPBio | 1mg | 564.28 Pln | |
| GLPBio | 10mg | 802.98 Pln | |
| GLPBio | 5mg | 657.89 Pln | |
| GLPBio | 10mM (in 1ml dmso) | 681.29 Pln | |
| GLPBio | 50mg | 1533.14 Pln |
properties
| purity | No data |
|---|---|
| delivery time | To be confirmed by Chemat |
Vamorolone is a 3-oxo-1,4-steroid that is pregna-1,4,9(11)-trien-17-ol substituted by oxo, oxo, and hydroxy groups at positions 3, 20, and 21, respectively. It is approved by the FDA for the treatment of patients with Duchenne muscular dystrophy aged 2 years and older. It has a role as an anti-inflammatory drug, an immunosuppressive agent and a glucocorticoid receptor agonist. It is a primary alpha-hydroxy ketone, a tertiary alpha-hydroxy ketone, a 17alpha-hydroxy steroid, a 21-hydroxy steroid, a 20-oxo steroid, a corticosteroid and a 3-oxo-Delta(1),Delta(4)-steroid.
Source: ChEBI
| Molecular formula | C22H28O4 |
|---|---|
| Molecular weight | 356.5 g/mol |
| IUPAC name | (8S,10S,13S,14S,16R,17R)-17-hydroxy-17-(2-hydroxyacetyl)-10,13,16-trimethyl-7,8,12,14,15,16-hexahydro-6H-cyclopenta[a]phenanthren-3-one |
| InChIKey | ZYTXTXAMMDTYDQ-DGEXFFLYSA-N |
| SMILES | C[C@@H]1C[C@H]2[C@@H]3CCC4=CC(=O)C=C[C@@]4(C3=CC[C@@]2([C@]1(C(=O)CO)O)C)C |
Computed by PubChem (NCBI)
Synonyms:
vamorolone, Agamree, vamorolona, 17,21-Dihydroxy-16alpha-methylpregna-1,4,9(11)-triene-3,20-dione, vamorolonum, 9,11-dehydro dexamethasone, (16alpha)-17,21-dihydroxy-16-methylpregna-1,4,9(11)-triene-3,20-dione, Vamorolone [USAN], Dexamethasone EP Impurity E, 16a-Methyl-9,11-dehydro Prednisolone