Products 13209-41-1
CAS 13209-41-1 appears in our catalog under these names: Vamorolone, Dexamethasone EP Impurity E, 16Alpha-Methyl-9,11-dehydro Prednisolone, >95% (HPLC), Vamorolone/ 98.04% (existing batch purity), 16a-Methyl-9,11-dehydro prednisolone - Bio-X â„¢. Offered by: GLPBio, Chemat Brand, TRC, Mikromol, TargetMol. Available pack sizes: 1mg, on request, 10mg, 25mg, 5mg, 50mg, 2mg, 100mg.
Vamorolone is a 3-oxo-1,4-steroid that is pregna-1,4,9(11)-trien-17-ol substituted by oxo, oxo, and hydroxy groups at positions 3, 20, and 21, respectively. It is approved by the FDA for the treatment of patients with Duchenne muscular dystrophy aged 2 years and older. It has a role as an anti-inflammatory drug, an immunosuppressive agent and a glucocorticoid receptor agonist. It is a primary alpha-hydroxy ketone, a tertiary alpha-hydroxy ketone, a 17alpha-hydroxy steroid, a 21-hydroxy steroid, a 20-oxo steroid, a corticosteroid and a 3-oxo-Delta(1),Delta(4)-steroid.
Source: ChEBI
| Molecular formula | C22H28O4 |
|---|---|
| Molecular weight | 356.5 g/mol |
| IUPAC name | (8S,10S,13S,14S,16R,17R)-17-hydroxy-17-(2-hydroxyacetyl)-10,13,16-trimethyl-7,8,12,14,15,16-hexahydro-6H-cyclopenta[a]phenanthren-3-one |
| InChIKey | ZYTXTXAMMDTYDQ-DGEXFFLYSA-N |
| SMILES | C[C@@H]1C[C@H]2[C@@H]3CCC4=CC(=O)C=C[C@@]4(C3=CC[C@@]2([C@]1(C(=O)CO)O)C)C |
Computed by PubChem (NCBI)
Synonyms:
vamorolone, Agamree, vamorolona, 17,21-Dihydroxy-16alpha-methylpregna-1,4,9(11)-triene-3,20-dione, vamorolonum, 9,11-dehydro dexamethasone, (16alpha)-17,21-dihydroxy-16-methylpregna-1,4,9(11)-triene-3,20-dione, Vamorolone [USAN], Dexamethasone EP Impurity E, 16a-Methyl-9,11-dehydro Prednisolone