Win 18446 (Standard)
cas: 1477-57-2 — see every product listed under this CAS number, including other names
Win 18446 (Standard) (CAS 1477-57-2) is a chemical reagent available from Chemat. Available pack sizes: 100 mg, 5 mg, 25 mg, 10 mg, 50 mg. Offered by: MedChemExpress.
| brand | MedChemExpress |
|---|---|
| catalog number | HY-W011094R-100 mg |
| cas | 1477-57-2 |
| size | 100 mg |
| availability | Get quote |
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Available pack sizes
| brand | size | price | |
|---|---|---|---|
| MedChemExpress | 100 mg | 1894.01 Pln | |
| MedChemExpress | 5 mg | 407.93 Pln | |
| MedChemExpress | 25 mg | 895.55 Pln | |
| MedChemExpress | 10 mg | 551.89 Pln | |
| MedChemExpress | 50 mg | 1294.93 Pln |
properties
| delivery time | over 3 weeks |
|---|---|
| purity | no data |
WIN 18446 is a carboxamide that is 1,8-diaminooctane in which a hydrogen attached to each of the amino groups has been replaced by a dichloroacetyl group. Inhibitor of aldehyde dehydrogenase 1a2 (ALDH1a2). Inhibits the biosynthesis of retinoic acid from retinol in neonatal and adult murine testis. It down-regulates sex related genes in zebrafish. It has a role as an EC 1.2.1.3 [aldehyde dehydrogenase (NAD(+))] inhibitor. It is a secondary carboxamide and an organochlorine compound. It is functionally related to a dichloroacetic acid and a 1,8-diaminooctane.
Source: ChEBI
| Molecular formula | C12H20Cl4N2O2 |
|---|---|
| Molecular weight | 366.1 g/mol |
| IUPAC name | 2,2-dichloro-N-[8-[(2,2-dichloroacetyl)amino]octyl]acetamide |
| InChIKey | FAOMZVDZARKPFJ-UHFFFAOYSA-N |
| SMILES | C(CCCCNC(=O)C(Cl)Cl)CCCNC(=O)C(Cl)Cl |
Computed by PubChem (NCBI)
Synonyms:
Fertilysin, Fertilysine, Win-18446, N,N'-Bis(dichloroacetyl)-1,8-octamethylenediamine, N,N'-Octamethylenebis(2,2-dichloroacetamide), N,N'-Bis(dichloroacetyl)-1,8-diaminooctane, N,N'-Bis(dichloracetyl)-1,8-octanediamine, N,N'-1,8-Octanediylbis(2,2-dichloroacetamide), N,N'-Octamethylenebis(2,2-dichloro-N-ethylacetamide), N,N'-octamethylene bis(2,2-dichloro)-N-ethylacetamide