WIN 18446
cas: 1477-57-2 — see every product listed under this CAS number, including other names
WIN 18446 (CAS 1477-57-2) is a chemical reagent available from Chemat. Available pack sizes: 10mg, 100mg, 25mg, 5mg, 50mg, 500mg, 250mg. Offered by: GLPBio, Biosynth.
| brand | GLPBio |
|---|---|
| catalog number | GC10438-10 |
| cas | 1477-57-2 |
| size | 10mg |
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Available pack sizes
| brand | size | price | |
|---|---|---|---|
| GLPBio | 10mg | 554.92 Pln | |
| GLPBio | 100mg | 859.15 Pln | |
| GLPBio | 25mg | 639.16 Pln | |
| GLPBio | 5mg | 512.79 Pln | |
| GLPBio | 50mg | 732.77 Pln | |
| GLPBio | 500mg | 1575.26 Pln | |
| Biosynth | 100mg | price on request | |
| Biosynth | 250mg | price on request | |
| Biosynth | 500mg | price on request |
properties
| purity | No data |
|---|---|
| delivery time | To be confirmed by Chemat |
WIN 18446 is a carboxamide that is 1,8-diaminooctane in which a hydrogen attached to each of the amino groups has been replaced by a dichloroacetyl group. Inhibitor of aldehyde dehydrogenase 1a2 (ALDH1a2). Inhibits the biosynthesis of retinoic acid from retinol in neonatal and adult murine testis. It down-regulates sex related genes in zebrafish. It has a role as an EC 1.2.1.3 [aldehyde dehydrogenase (NAD(+))] inhibitor. It is a secondary carboxamide and an organochlorine compound. It is functionally related to a dichloroacetic acid and a 1,8-diaminooctane.
Source: ChEBI
| Molecular formula | C12H20Cl4N2O2 |
|---|---|
| Molecular weight | 366.1 g/mol |
| IUPAC name | 2,2-dichloro-N-[8-[(2,2-dichloroacetyl)amino]octyl]acetamide |
| InChIKey | FAOMZVDZARKPFJ-UHFFFAOYSA-N |
| SMILES | C(CCCCNC(=O)C(Cl)Cl)CCCNC(=O)C(Cl)Cl |
Computed by PubChem (NCBI)
Synonyms:
Fertilysin, Fertilysine, Win-18446, N,N'-Bis(dichloroacetyl)-1,8-octamethylenediamine, N,N'-Octamethylenebis(2,2-dichloroacetamide), N,N'-Bis(dichloroacetyl)-1,8-diaminooctane, N,N'-Bis(dichloracetyl)-1,8-octanediamine, N,N'-1,8-Octanediylbis(2,2-dichloroacetamide), N,N'-Octamethylenebis(2,2-dichloro-N-ethylacetamide), N,N'-octamethylene bis(2,2-dichloro)-N-ethylacetamide