Products 1477-57-2

CAS 1477-57-2 appears in our catalog under these names: Win 18446, >95% (HPLC), WIN 18446/ 98.41% (existing batch purity), WIN 18446, WIN 18446, WIN18446 95%. Offered by: TRC, TargetMol, GLPBio, Biosynth, Ambeed. Available pack sizes: 10mg, 50mg, 1g, 25mg, 100mg, 500mg, 5mg, 250mg.

Win 18446, >95% (HPLC)
TRC
  • size: 10mg, 50mg
  • Variants: 2
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WIN 18446/ 98.41% (existing batch purity)
TargetMol
  • size: 1g, 25mg, 50mg, 100mg
  • Variants: 5
from 412.42
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WIN 18446
GLPBio
  • size: 10mg, 100mg, 25mg, 5mg
  • Variants: 6
from 512.79
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WIN 18446
Biosynth
  • size: 100mg, 250mg, 500mg
  • Variants: 3
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WIN18446 95%
Ambeed
  • size: 100mg, 250mg, 1g, 5g
  • Variants: 5
from 186.81
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N,N'-(Octane-1,8-diyl)bis(2,2-dichloroacetamide), 95%, 95%
Chemat
  • size: 100mg, 250mg, 1g, 5g
  • Variants: 5
from 126.80
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Win 18446, 98.94%
MedChemExpress
  • size: 100 mg, 10mM/1mL, 500 mg, 50 mg
  • Variants: 4
from 407.93
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Win 18446 (Standard)
MedChemExpress
  • size: 100 mg, 5 mg, 25 mg, 10 mg
  • Variants: 5
from 407.93
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N,N'-Octamethylenebis(dichloroacetamide), 95%
Fluorochem
  • size: 100mg, 250mg, 1g, 5g
  • Variants: 5
from 206.20
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Structural formula: {0} (CAS {1})

WIN 18446 is a carboxamide that is 1,8-diaminooctane in which a hydrogen attached to each of the amino groups has been replaced by a dichloroacetyl group. Inhibitor of aldehyde dehydrogenase 1a2 (ALDH1a2). Inhibits the biosynthesis of retinoic acid from retinol in neonatal and adult murine testis. It down-regulates sex related genes in zebrafish. It has a role as an EC 1.2.1.3 [aldehyde dehydrogenase (NAD(+))] inhibitor. It is a secondary carboxamide and an organochlorine compound. It is functionally related to a dichloroacetic acid and a 1,8-diaminooctane.

Source: ChEBI

Identity
Molecular formulaC12H20Cl4N2O2
Molecular weight366.1 g/mol
IUPAC name2,2-dichloro-N-[8-[(2,2-dichloroacetyl)amino]octyl]acetamide
InChIKeyFAOMZVDZARKPFJ-UHFFFAOYSA-N
SMILESC(CCCCNC(=O)C(Cl)Cl)CCCNC(=O)C(Cl)Cl

Computed by PubChem (NCBI)

Synonyms: Fertilysin, Fertilysine, Win-18446, N,N'-Bis(dichloroacetyl)-1,8-octamethylenediamine, N,N'-Octamethylenebis(2,2-dichloroacetamide), N,N'-Bis(dichloroacetyl)-1,8-diaminooctane, N,N'-Bis(dichloracetyl)-1,8-octanediamine, N,N'-1,8-Octanediylbis(2,2-dichloroacetamide), N,N'-Octamethylenebis(2,2-dichloro-N-ethylacetamide), N,N'-octamethylene bis(2,2-dichloro)-N-ethylacetamide