Z-DEVD-FMK, 98.0%
cas: 210344-95-9 — see every product listed under this CAS number, including other names
Z-DEVD-FMK, 98.0% (CAS 210344-95-9) is a chemical reagent available from Chemat. Available pack sizes: 1 mg, 10mM/1mL, 10 mg, 5 mg. Offered by: MedChemExpress.
| brand | MedChemExpress |
|---|---|
| catalog number | HY-12466-1 mg |
| cas | 210344-95-9 |
| size | 1 mg |
| availability | In stock |
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Available pack sizes
| brand | size | price | |
|---|---|---|---|
| MedChemExpress | 1 mg | 435.79 Pln | |
| MedChemExpress | 10mM/1mL | 1383.17 Pln | |
| MedChemExpress | 10 mg | 1555.00 Pln | |
| MedChemExpress | 5 mg | 979.14 Pln |
properties
| delivery time | 1-2 weeks |
|---|---|
| purity | 98.0% |
Z-DEVD-FMK is a tetrapeptide consisting of Fmoc-L-aspartic acid 4-methyl ester, methyl L-alpha-glutamic acid 5-methyl ester, L-valine and the fluoromethyl ketone derived from the 1-carboxy group of L-aspartic acid 4-methyl ester coupled in sequence. It is a specific, irreversible caspase-3 inhibitor that also shows potent inhibition of caspase-6, caspase-7, caspase-8, and caspase-10. It has a role as an EC 3.4.22.56 (caspase-3) inhibitor, a neuroprotective agent and an apoptosis inhibitor.
Source: ChEBI
| Molecular formula | C30H41FN4O12 |
|---|---|
| Molecular weight | 668.7 g/mol |
| IUPAC name | methyl (4S)-5-[[(2S)-1-[[(3S)-5-fluoro-1-methoxy-1,4-dioxopentan-3-yl]amino]-3-methyl-1-oxobutan-2-yl]amino]-4-[[(2S)-4-methoxy-4-oxo-2-(phenylmethoxycarbonylamino)butanoyl]amino]-5-oxopentanoate |
| InChIKey | GBJVAVGBSGRRKN-JYEBCORGSA-N |
| SMILES | CC(C)[C@@H](C(=O)N[C@@H](CC(=O)OC)C(=O)CF)NC(=O)[C@H](CCC(=O)OC)NC(=O)[C@H](CC(=O)OC)NC(=O)OCC1=CC=CC=C1 |
Computed by PubChem (NCBI)
Synonyms:
Z-DEVD-FMK, benzyloxycarbonyl-Asp(OMe)-Glu(OMe)-Val-Asp(OMe)-fluoromethylketone, N-benzyloxycarbonyl-Asp(OMe)-Glu(OMe)-Val-Asp(OMe)-fluoromethyl ketone, benzoylcarbonyl-aspartyl-glutamyl-valyl-aspartyl-fluoromethyl ketone, Z-Asp-Glu-Val-Asp-fluoromethyl ketone, Caspase-3 Inhibitor, Z-Asp(OMe)-Glu(OMe)-Val-DL-Asp(OMe)-fluoromethylketone, Z-Asp(OMe)-Glu(OMe)-Val-Asp(OMe)-Fluoromethylketone, Z-D(OMe)E(Ome)VD(OMe)-FMK, Z-DEVD-fluoromethylketone