Z-Devd-fmk, 95%

cas: 210344-95-9 — see every product listed under this CAS number, including other names

Z-Devd-fmk, 95% (CAS 210344-95-9) is a chemical reagent available from Chemat. Available pack sizes: 1mg, 25mg, 10mg, 5mg. Offered by: Combi-blocks.

brandCombi-blocks
catalog numberHD-8977-1mg
cas210344-95-9
size1mg
Documents: Safety Data Sheet (MSDS)
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Available pack sizes

brand size price
Combi-blocks 1mg price on request
Combi-blocks 25mg price on request
Combi-blocks 10mg price on request
Combi-blocks 5mg price on request

properties

purity95%
delivery time1-2 weeks (only if in stock, to check click on availability)
Structural formula: {0} (CAS {1})

Z-DEVD-FMK is a tetrapeptide consisting of Fmoc-L-aspartic acid 4-methyl ester, methyl L-alpha-glutamic acid 5-methyl ester, L-valine and the fluoromethyl ketone derived from the 1-carboxy group of L-aspartic acid 4-methyl ester coupled in sequence. It is a specific, irreversible caspase-3 inhibitor that also shows potent inhibition of caspase-6, caspase-7, caspase-8, and caspase-10. It has a role as an EC 3.4.22.56 (caspase-3) inhibitor, a neuroprotective agent and an apoptosis inhibitor.

Source: ChEBI

Identity
Molecular formulaC30H41FN4O12
Molecular weight668.7 g/mol
IUPAC namemethyl (4S)-5-[[(2S)-1-[[(3S)-5-fluoro-1-methoxy-1,4-dioxopentan-3-yl]amino]-3-methyl-1-oxobutan-2-yl]amino]-4-[[(2S)-4-methoxy-4-oxo-2-(phenylmethoxycarbonylamino)butanoyl]amino]-5-oxopentanoate
InChIKeyGBJVAVGBSGRRKN-JYEBCORGSA-N
SMILESCC(C)[C@@H](C(=O)N[C@@H](CC(=O)OC)C(=O)CF)NC(=O)[C@H](CCC(=O)OC)NC(=O)[C@H](CC(=O)OC)NC(=O)OCC1=CC=CC=C1

Computed by PubChem (NCBI)

Synonyms: Z-DEVD-FMK, benzyloxycarbonyl-Asp(OMe)-Glu(OMe)-Val-Asp(OMe)-fluoromethylketone, N-benzyloxycarbonyl-Asp(OMe)-Glu(OMe)-Val-Asp(OMe)-fluoromethyl ketone, benzoylcarbonyl-aspartyl-glutamyl-valyl-aspartyl-fluoromethyl ketone, Z-Asp-Glu-Val-Asp-fluoromethyl ketone, Caspase-3 Inhibitor, Z-Asp(OMe)-Glu(OMe)-Val-DL-Asp(OMe)-fluoromethylketone, Z-Asp(OMe)-Glu(OMe)-Val-Asp(OMe)-Fluoromethylketone, Z-D(OMe)E(Ome)VD(OMe)-FMK, Z-DEVD-fluoromethylketone

Also listed as

Z-DEVD-FMK/ 99.69% (existing batch purity) TargetMol CAS 210344-95-9
Z–DEVD–FMK GLPBio CAS 210344-95-9
Z-Asp(OMe)-Glu(OMe)-Val-DL-Asp(OMe)-fluoromethylketone Biosynth CAS 210344-95-9
Z-DEVD-FMK 98% Ambeed CAS 210344-95-9
Caspase-3 Inhibitor II 1PC X 1MG Sigma-Aldrich CAS 210344-95-9
Caspase-3 Inhibitor II 1PC X 250UG Sigma-Aldrich CAS 210344-95-9
Caspase-3 Inhibitor II 1PC X 5UNMG Sigma-Aldrich CAS 210344-95-9
Caspase-3 Inhibitor, 98%, 98% Chemat CAS 210344-95-9
Z-DEVD-FMK, 98.0% MedChemExpress CAS 210344-95-9