Products 1038915-58-0
CAS 1038915-58-0 appears in our catalog under these names: ent-Niraparib, Niraparib (R-enantiomer)/ 99.41% (existing batch purity), (R)-2-(4-(Piperidin-3-yl)phenyl)-2H-indazole-7-carboxamide, 99%, 99%, Niraparib (R-enantiomer), 99.45%. Offered by: Chemat Brand, TargetMol, Biosynth, Chemat, MedChemExpress. Available pack sizes: on request, 1mg, 5mg, 10mg, 25mg, 50mg, 100mg, 200mg.
2-{4-[(3R)-piperidin-3-yl]phenyl}-2H-indazole-7-carboxamide is a 2-[4-(piperidin-3-yl)phenyl]-2H-indazole-7-carboxamide that has R-configuration. It is a potent PARP1 inhibitor with IC50 of 2.4 nM. It has a role as an antineoplastic agent and an EC 2.4.2.30 (NAD(+) ADP-ribosyltransferase) inhibitor.
Source: ChEBI
| Molecular formula | C19H20N4O |
|---|---|
| Molecular weight | 320.4 g/mol |
| IUPAC name | 2-[4-[(3R)-piperidin-3-yl]phenyl]indazole-7-carboxamide |
| InChIKey | PCHKPVIQAHNQLW-AWEZNQCLSA-N |
| SMILES | C1C[C@@H](CNC1)C2=CC=C(C=C2)N3C=C4C=CC=C(C4=N3)C(=O)N |
Computed by PubChem (NCBI)
Synonyms:
Niraparib (R-enantiomer), Niraparib R-enantiomer, (R)-2-(4-(piperidin-3-yl)phenyl)-2H-indazole-7-carboxamide, ent-niraparib, (R)-NIRAPARIB, 2-[4-[(3R)-piperidin-3-yl]phenyl]indazole-7-carboxamide, 2-{4-[(3r)-piperidin-3-yl]phenyl}-2h-indazole-7-carboxamide, 2-[4-(3R)-3-piperidinylphenyl]-2H-indazole-7-carboxamide, Niraparib, (R)-, orb1309416