Products 1038915-75-1

CAS 1038915-75-1 appears in our catalog under these names: 2-[4-(Piperidin-3-yl)phenyl]-2h-indazole-7-carboxamide, 95%, 2-(4-(Piperidin-3-yl)phenyl)-2H-indazole-7-carboxamide, 97%, MK-4827 Racemate, MK–4827 Racemate, 2-(4-(Piperidin-3-yl)phenyl)-2H-indazole-7-carboxamide. Offered by: Combi-blocks, AmBeed, TargetMol, GLPBio, Biosynth. Available pack sizes: 100mg, 1g, 250mg, 5g, 2mg, 5mg, 10mg, 25mg.

Structural formula: {0} (CAS {1})

2-[4-(piperidin-3-yl)phenyl]-2H-indazole-7-carboxamide is a member of the class of indazoles that is 2H-indazole substituted by 4-(piperidin-3-yl)phenyl and aminocarbonyl groups at positions 2 and 7, respectively. It is a potent PARP1 inhibitor with IC50 of 3.2 nM. It has a role as an antineoplastic agent and an EC 2.4.2.30 (NAD(+) ADP-ribosyltransferase) inhibitor. It is a primary carboxamide, a member of benzenes, a member of piperidines and a member of indazoles.

Source: ChEBI

Identity
Molecular formulaC19H20N4O
Molecular weight320.4 g/mol
IUPAC name2-(4-piperidin-3-ylphenyl)indazole-7-carboxamide
InChIKeyPCHKPVIQAHNQLW-UHFFFAOYSA-N
SMILESC1CC(CNC1)C2=CC=C(C=C2)N3C=C4C=CC=C(C4=N3)C(=O)N

Computed by PubChem (NCBI)