Products 1042385-75-0

CAS 1042385-75-0 appears in our catalog under these names: Dacomitinib, 95%, Dacomitinib hydrate/ 98.05% (existing batch purity), Dacomitinib hydrate, Dacomitinib hydrate 98%, (E)-N-(4-((3-Chloro-4-fluorophenyl)amino)-7-methoxyquinazolin-6-yl)-4-(piperidin-1-yl)but-2-enamide hydrate, 99%, 99%. Offered by: Combi-blocks, TargetMol, GLPBio, Ambeed, Chemat. Available pack sizes: 100mg, 250mg, 1g, 5mg, 10mg, 25mg, 50mg, 200mg.

Dacomitinib, 95%
Combi-blocks
  • size: 100mg, 250mg, 1g
  • Variants: 3
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Dacomitinib hydrate/ 98.05% (existing batch purity)
TargetMol
  • size: 5mg, 10mg, 25mg, 50mg
  • Variants: 6
from 465.53
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Dacomitinib hydrate
GLPBio
  • size: 10mg, 100mg, 5mg, 50mg
  • Variants: 4
from 793.62
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Dacomitinib hydrate 98%
Ambeed
  • size: 100mg, 250mg, 1g, 5g
  • Variants: 4
from 175.69
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(E)-N-(4-((3-Chloro-4-fluorophenyl)amino)-7-methoxyquinazolin-6-yl)-4-(piperidin-1-yl)but-2-enamide hydrate, 99%, 99%
Chemat
  • size: 100mg, 250mg, 1g, 5g
  • Variants: 8
from 107.60
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Dacomitinib (hydrate), 99.54%
MedChemExpress
  • size: 10 mg, 50 mg, 5 mg, 100 mg
  • Variants: 4
from 551.89
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Structural formula: {0} (CAS {1})

Dacomitinib is a member of the class of quinazolines that is 7-methoxyquinazoline-4,6-diamine in which the amino group at position 4 is substituted by a 3-chloro-4-fluorophenyl group and the amino group at position 6 is substituted by an (E)-4-(piperidin-1-yl)but-2-enoyl group. It has a role as an antineoplastic agent and an epidermal growth factor receptor antagonist. It is a secondary carboxamide, a member of piperidines, a member of quinazolines, a secondary amino compound, a tertiary amino compound, an enamide, a member of monochlorobenzenes and a member of monofluorobenzenes.

Source: ChEBI

Identity
Molecular formulaC24H25ClFN5O2
Molecular weight469.9 g/mol
IUPAC name(E)-N-[4-(3-chloro-4-fluoroanilino)-7-methoxyquinazolin-6-yl]-4-piperidin-1-ylbut-2-enamide
InChIKeyLVXJQMNHJWSHET-AATRIKPKSA-N
SMILESCOC1=C(C=C2C(=C1)N=CN=C2NC3=CC(=C(C=C3)F)Cl)NC(=O)/C=C/CN4CCCCC4

Computed by PubChem (NCBI)

Synonyms: Dacomitinib, Dacomitinib anhydrous, dacomitinibum, Vizimpro, pf00299804, EGFR Inhibitor PF-00299804, Dacomitinib (PF299804, PF299), Dacomitinib (PF299804), Dacomitinib [USAN:INN], Dacomitinib (INN)