Products 131740-09-5

CAS 131740-09-5 appears in our catalog under these names: Flavopiridol Hydrochloride, Flavopiridol hydrochloride/ 99.88% (existing batch purity), Flavopiridol hydrochloride, Flavopiridol HCl 98%, FLAVOPIRIDOL HYDROCHLORIDE HYDRATE&. Offered by: TRC, TargetMol, GLPBio, Biosynth, Ambeed. Available pack sizes: 10mg, 50mg, 5mg, 100mg, 1g, 25mg, 10mM (in 1ml dmso), 0,5g.

Flavopiridol Hydrochloride
TRC, Biosynth
  • size: 10mg, 50mg, 5mg, 0,5g
  • Variants: 5
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Flavopiridol hydrochloride/ 99.88% (existing batch purity)
TargetMol
  • size: 5mg, 10mg
  • Variants: 2
from 472.23
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Flavopiridol hydrochloride
GLPBio
  • size: 10mg, 100mg, 1g, 25mg
  • Variants: 5
from 587.68
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Flavopiridol HCl 98%
Ambeed
  • size: 1mg, 5mg, 10mg, 50mg
  • Variants: 5
from 192.38
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FLAVOPIRIDOL HYDROCHLORIDE HYDRATE&
Sigma-Aldrich
  • size: 25MG, 5MG
  • Variants: 2
from 969.00
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Flavopiridol hydrochloride, 98%, 98%
Chemat
  • size: 1mg, 5mg
  • Variants: 2
from 131.60
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Flavopiridol (Hydrochloride), 99.73%
MedChemExpress
  • size: 5 mg, 50 mg, 10 mg, 100 mg
  • Variants: 7
from 384.71
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2-(2-Chlorophenyl)-5,7-dihydroxy-8-((3S,4R)-3-hydroxy-1-methylpiperidin-4-yl)-4H-chromen-4-one hydrochloride, 98%
Fluorochem
  • size: 1mg, 5mg
  • Variants: 2
from 227.02
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Structural formula: {0} (CAS {1})

Alvocidib hydrochloride is a hydrochloride salt resulting from the formal reaction of equimolar amounts of alvocidib and hydrogen chloride. A cyclin-dependent kinase 9 (CDK9) inhibitor, it has been studied for the treatment of acute myeloid leukaemia, arthritis and atherosclerotic plaque formation. It has a role as an antineoplastic agent, an antirheumatic drug, an apoptosis inducer and an EC 2.7.11.22 (cyclin-dependent kinase) inhibitor. It contains an alvocidib(1+).

Source: ChEBI

Identity
Molecular formulaC21H21Cl2NO5
Molecular weight438.3 g/mol
IUPAC name2-(2-chlorophenyl)-5,7-dihydroxy-8-[(3S,4R)-3-hydroxy-1-methylpiperidin-4-yl]chromen-4-one;hydrochloride
InChIKeyLGMSNQNWOCSPIK-LWHGMNCYSA-N
SMILESCN1CC[C@@H]([C@@H](C1)O)C2=C(C=C(C3=C2OC(=CC3=O)C4=CC=CC=C4Cl)O)O.Cl

Computed by PubChem (NCBI)

Synonyms: Flavopiridol hydrochloride, Alvocidib hydrochloride, Flavopiridol HCl, Alvocidib hydrochloride [USAN], Flavopiridol (Hydrochloride), Alvocidib [USAN:INN:BAN], Alvocidib hydrochloride (USAN), Flavopiridol HC, Alvocidib HCl, orb1226551
Isomers (same molecular formula)
2-(2-chlorophenyl)-5,7-dihydroxy-8-[(2R,3S)-2-(hydroxymethyl)-1-methylpyrrolidin-3-yl]chromen-4-one;hydrochloride C21H21Cl2NO5