Products 1337532-29-2

CAS 1337532-29-2 appears in our catalog under these names: GSK2656157, >95% (HPLC), GSK2656157/ 99.89% (existing batch purity), GSK2656157, GSK2656157 98%, GSK2656157, 98%, 98%. Offered by: TRC, TargetMol, GLPBio, Ambeed, Chemat. Available pack sizes: 10mg, 2mg, 5mg, 25mg, 50mg, 100mg, 200mg, 10mM (in 1ml dmso).

GSK2656157, >95% (HPLC)
TRC
  • size: 10mg
  • Variants: 1
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GSK2656157/ 99.89% (existing batch purity)
TargetMol
  • size: 2mg, 5mg, 10mg, 25mg
  • Variants: 7
from 399.00
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GSK2656157
GLPBio
  • size: 10mg, 100mg, 10mM (in 1ml dmso), 50mg
  • Variants: 4
from 826.38
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GSK2656157 98%
Ambeed
  • size: 5mg, 10mg, 25mg, 50mg
  • Variants: 6
from 531.69
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GSK2656157, 98%, 98%
Chemat
  • size: 5mg, 10mg, 25mg, 50mg
  • Variants: 6
from 314.00
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GSK2656157, 99.66%
MedChemExpress
  • size: 10 mg, 100 mg, 10mM/1mL, 5 mg
  • Variants: 5
from 384.71
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Structural formula: {0} (CAS {1})

GSK2656157 is a pyrrolopyrimidine that is 7-methyl-7H-pyrrolo[2,3-d]pyrimidin-4-amine which has been substituted at position 5 by a 4-fluoro-2,3-dihydro-1H-indol-5-yl group, the nitrogen of which has been acylated by a (6-methylpyridin-2-yl)acetyl group. An orally bioavailable PERK inhibitor. It has a role as a PERK inhibitor, an EC 3.1.3.48 (protein-tyrosine-phosphatase) inhibitor and an antineoplastic agent. It is a tertiary carboxamide, a member of indoles, a member of methylpyridines, an organofluorine compound, a pyrrolopyrimidine and a biaryl.

Source: ChEBI

Identity
Molecular formulaC23H21FN6O
Molecular weight416.5 g/mol
IUPAC name1-[5-(4-amino-7-methylpyrrolo[2,3-d]pyrimidin-5-yl)-4-fluoro-2,3-dihydroindol-1-yl]-2-(6-methyl-2-pyridinyl)ethanone
InChIKeyPRWSIEBRGXYXAJ-UHFFFAOYSA-N
SMILESCC1=NC(=CC=C1)CC(=O)N2CCC3=C2C=CC(=C3F)C4=CN(C5=NC=NC(=C45)N)C

Computed by PubChem (NCBI)

Synonyms: PERK inhibitor GSK2656157, PRWSIEBRGXYXAJ-UHFFFAOYSA-N, orb1226516, orb1305213, PERK inhibitor GSK2656157?, s7033, compound 6 [PMID: 24900593]