Products 134381-21-8
CAS 134381-21-8 appears in our catalog under these names: Epoxomicin, 95%, Epoxomicin, Epoxomicin/ 99.91% (existing batch purity), Epoxomicin, 98.00%, Epoxomicin 95%. Offered by: Combi-blocks, GLPBio, TargetMol, Biosynth, Chemat. Available pack sizes: 250mg, 1mg, 20mg, 5mg, 10mM (in 1ml dmso), 10mg, 25mg, 50mg.
Epoxomicin is a tripeptide consisting of an Ile-Ile-Thr-NH2 sequence N-substituted on the threonamide amidic nitrogen with a (2S)-4-methyl-1-[(2R)-2-methyloxiran-2-yl]-1-oxopentan-2-yl group and with acetyl and methyl groups on the nitrogen of the isoleucine residue distal to the threonamide; a naturally occurring selective proteasome inhibitor with anti-inflammatory activity. It has a role as a proteasome inhibitor. It is a member of morpholines and a tripeptide.
Source: ChEBI
| Molecular formula | C28H50N4O7 |
|---|---|
| Molecular weight | 554.7 g/mol |
| IUPAC name | (2S,3S)-2-[[(2S,3S)-2-[acetyl(methyl)amino]-3-methylpentanoyl]amino]-N-[(2S,3R)-3-hydroxy-1-[[(2S)-4-methyl-1-[(2R)-2-methyloxiran-2-yl]-1-oxopentan-2-yl]amino]-1-oxobutan-2-yl]-3-methylpentanamide |
| InChIKey | DOGIDQKFVLKMLQ-JTHVHQAWSA-N |
| SMILES | CC[C@H](C)[C@@H](C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CC(C)C)C(=O)[C@]1(CO1)C)NC(=O)[C@H]([C@@H](C)CC)N(C)C(=O)C |
Computed by PubChem (NCBI)