Products 142273-20-9
CAS 142273-20-9 appears in our catalog under these names: Kenpaullone, KenPaullone/ 98%, Kenpaullone, >97.0%(HPLC), Kenpaullone 98%, Kenpaullone 1PC X 1MG. Offered by: TRC, GLPBio, TargetMol, Biosynth, TCI. Available pack sizes: 100mg, 10mg, 5mg, 10mM (in 1ml dmso), 1mg, 2mg, 25mg, 50mg.
Kenpaullone is an indolobenzazepine that is paullone in which the hydrogen at position 9 is replaced by a bromo substituent. It is an ATP-competitive inhibitor of cyclin-dependent kinases (CDKs) and glycogen synthase kinase 3beta (GSK3beta). It has a role as a geroprotector, a cardioprotective agent, an EC 2.7.11.22 (cyclin-dependent kinase) inhibitor and an EC 2.7.11.26 (tau-protein kinase) inhibitor. It is an indolobenzazepine, a lactam and an organobromine compound. It is functionally related to a paullone.
Source: ChEBI
| Molecular formula | C16H11BrN2O |
|---|---|
| Molecular weight | 327.17 g/mol |
| IUPAC name | 9-bromo-7,12-dihydro-5H-indolo[3,2-d][1]benzazepin-6-one |
| InChIKey | QQUXFYAWXPMDOE-UHFFFAOYSA-N |
| SMILES | C1C2=C(C3=CC=CC=C3NC1=O)NC4=C2C=C(C=C4)Br |
Computed by PubChem (NCBI)
Synonyms:
kenpaullone, 9-Bromopaullone, 9-Bromo-7,12-dihydroindolo[3,2-d][1]benzazepin-6(5H)-one, 9-Bromo-7,12-dihydroindolo(3,2-d)(1)benzazepin-6(5H)-one, 9-bromo-5,12-dihydro-7H-benzo(2,3)azepino(4,5-b)indol-6-one, 9-bromo-7,12-dihydrobenzo[2,3]azepino[4,5-b]indol-6(5H)-one, Indolo[3,2-d][1]benzazepin-6(5H)-one, 9-bromo-7,12-dihydro-, 9-bromo-7,12-dihydro-5H-indolo[3,2-d][1]benzazepin-6-one, 9-Bromopaullone;NSC-664704, 9-Bromo-7,12-dihydro-indolo[3,2-d][1]benzazepin-6(5H)-one